How Well Does Shingrix Work
Two doses of Shingrix provide strong protection against shingles and postherpetic neuralgia , the most common complication of shingles.
- In adults 50 to 69 years old with healthy immune systems, Shingrix was 97% effective in preventing shingles in adults 70 years and older, Shingrix was 91% effective.
- In adults 50 years and older, Shingrix was 91% effective in preventing PHN in adults 70 years and older, Shingrix was 89% effective.
- In adults with weakened immune systems, Shingrix was between 68% and 91% effective in preventing shingles, depending on their underlying immunocompromising condition.
In people 70 years and older who had healthy immune systems, Shingrix immunity remained high throughout 7 years following vaccination.
How Do I Protect Myself From Shingles
The best protection from shingles is vaccination. People can still get shingles after receiving the varicella vaccine but they are 4 to 12 times less likely to do so than if they haven’t been immunized. The vaccine is recommended for most people 60 and older.
Some people should not receive the vaccine for example, those with certain allergies or who are taking certain medications. A health professional can advise who should not be vaccinated due to contraindications to the vaccine.
People between 50 and 59 years can request the vaccine from their health professional.
Shingles Is A Painful Blistering Rash That Often Develops In A Stripe That Wraps Around One Side Of The Body Or Face Besides The Rash Symptoms Include Fever Headache And Chills But Mainly You Hear About The Rash Because It Hurts
If youre over 50, the shingles vaccine Shingrix can help you avoid this super painful condition. And you might be surprised to learn who should get it:
If you already got the one-dose shingles vaccine , its time to upgrade to the newer model, Shingrix.
If you previously couldnt get the shingles shot because you are immunocompromised, you can and should get the new one, Shingrix.
You should also get the shingles vaccine if youve had shingles.
You should also get the shingles vaccine if you dont remember having chickenpox.
The varicella vaccine for children will prevent shingles later in life. This one is often combined with the measles-mumps-rubella vaccine and given around ages 1 and 5.
Symptoms, treatment, & epidemiology
Early shingles symptoms include tingling, burning, itching, or shooting pain in a localized area. Then after 1-14 days, a blistery rash appears. The blisters will scab over after about a week.
Shingles is treated with antiviral medication and with pain relievers. The antivirals are most effective when theyre started early on, so dont wait for it to get better on its own before seeking help.
1 in 3 adults will get shingles at some point in their lives. Some people are hospitalized with shingles, particularly when it attacks the nerves of the eye, ear, brain, or lungs. 10-15% of people who get shingles have nerve pain for weeks, months, or even longer after a shingles attack. This is called postherpetic neuralgia.
Shingles: deep cover agent
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Shingles On Your Buttocks
You can get a shingles rash on your buttocks. Shingles usually only affects one side of your body, so you may have a rash on one buttock but not the other.
As with other areas of the body, shingles on your buttocks may cause initial symptoms like tingling, itching, or pain.
After a few days, a red rash or blisters may develop. Some people experience pain but dont develop a rash.
. After the varicella-zoster virus initially reactivates, your skin may:
Shingles usually develops on one side of your body, often on your waist, back, or chest.
Within about 5 days, you may see a red rash in that area. Small groups of oozing, fluid-filled blisters may appear a few days later in the same area. You may experience flu-like symptoms such as a fever, headache, or fatigue.
During the next 10 days or so, the blisters will dry up and form scabs. The scabs will clear after a couple of weeks. After the scabs clear, some people continue to experience pain. This is called postherpetic neuralgia.
What Vaccines Can Help Prevent Shingles
There is currently one vaccine available in the U.S. to prevent shingles. Shingrix was approved in 2017 and it is more than 90% effective in preventing shingles. With Shingrix, you get two shots between 2 and 6 months apart and protection lasts an estimated 4-5 years. Doctors recommend it for healthy people over 50 as well as those 19 years of age and older who are or will be immunodeficient or immunosuppressed due to disease or therapy..
An earlier vaccine called Zostavax was removed from the market in 2020. That vaccine used a weak form of the chickenpox virus to send your bodyâs immune system into action to fight the disease. Shingrix does not. If you received the Zostavax vaccine, it is recommended that you also receive Shingrix.
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What Is The Shingles Vaccine
The shingles vaccine can protect you against shingles and postherpetic neuralgia , which is the most common complication of shingles. Shingles is a painful rash caused by the varicella-zoster virus, the same virus that causes chickenpox. The rash usually develops on one side of your body or face. It starts with red bumps and then the bumps turn into fluid-filled blisters.
How Do People Get Shingles
People get shingles when the virus that causes chicken pox, varicella zoster, is reactivated in their body. The varicella zoster virus doesn’t leave the body, even after a person has recovered from chicken pox. It can flare up again, causing shingles, often many years after a person has had chicken pox. The virus tends to reactivate when a person’s immune system is weakened because of another health problem.
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Vaccinate To Decrease Your Shingles Risk
Your chances of getting shingles increase as you get older. The U.S. Centers for Disease Control and Prevention recommends that adults age 50 and older get vaccinated against shingles.
Two vaccines, recombinant zoster vaccine and zoster vaccine live are available in the United States to prevent shingles. Shingrix is the preferred vaccine.
The CDC recommends Shingrix for adults 50 years and older, whether or not they have already had shingles or previously received the Zostavaxvaccine, which has been used since 2006. You should get two doses of Shingrix, two to six months apart. Two doses of Shingrix are more than 90% effective at preventing shingles. Shingrix is also 90% effective in helping to prevent PHN in those who get shingles despite being vaccinated.
While Zostavax is still available, studies show it is less effective than Shingrix.Zostavax may be used in some healthy adults 60 years and older, for example, in those who are allergic to Shingrix.
There is no specific time that you must wait after having shingles before receiving the shingles vaccine. But its probably best to hold off until the shingles rash has disappeared before getting vaccinated.
About the Author
Urmila Parlikar, Associate Director, Digital Health Products, Harvard Health Publishing
Should You Get Shingrix If You Had The Zostavax Shingles Vaccine
It is recommended that you get two doses of Shingrix even if you got a different shingles vaccine in the past. Before Shingrix was approved, the Zostavax shingles vaccine was available. It was discontinued in November 2020 as Shingrix is much more effective. If you had the Zostavax vaccine, talk to your healthcare provider about getting Shingrix.
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Do I Need To Pay For Shingles Immunisation
Vaccines covered by the NIP are free for people who are eligible. See the NIP Schedule to find out which vaccines you or your family are eligible to receive.
Eligible people get the vaccine for free, but your health care provider may charge a consultation fee for the visit. You can check this when you make your appointment.
If you are not eligible for free vaccine, you may need to pay for it. The cost depends on the type of vaccine, the formula and where you buy it from. Your immunisation provider can give you more information.
Available Vaccines And Vaccination Campaigns
Since 2008, the U.S. Advisory Committee on Immunization Practices has recommended most Americans aged 60 and older get the shingles vaccine. A newer recommendation was issued in 2018 with the licensure of a new vaccine: .
In adults 50-69 years old, Shingrix reduces the risk of shingles by more than 96%. For those 70 and older, the vaccine is 91.3% effective at preventing shingles. It similarly reduces the risk of post-herpetic neuralgia. Modeling studies project that protection will wane to 0 by 19 years after immunization. Study of the expected duration of protection is ongoing.
The antigen in Shingrix is a surface protein of the varicella zoster virus produced by culturing genetically engineered Chinese hamster ovary cells. Vaccination consists of two doses of vaccine, given at months 0 and 2-6.
The older shingles vaccine is a live, attenuated vaccine. It was licensed in 2006. The generic name of the vaccine is Zoster Vaccine, Live . It is still available, although Shingrix is recommended over Zostavax because of its superior effectiveness and duration of protection.
People who have previously been vaccinated with Zostavax are recommended to vaccinate with Shingrix.
Most Medicare drug plans cover the cost of the shingle vaccine and its administration, minus any copayments, for people 65 and older. Most private insurance plans provide coverage for the vaccination for people 50 and older.
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Guidance On Reporting Adverse Events Following Immunization
Vaccine providers are asked to report AEFIs through local public health officials and to follow AEFI reporting requirements that are specific to their province or territory. In general, any serious or unexpected adverse event felt to be temporally related to vaccination should be reported.
For LZV the following AEFIs are also of particular interest and should be reported:
- Suspected transmission of vaccine-strain virus to a close household or occupational contact. This phenomenon has been documented following varicella vaccine but it is rare, and transmission has not been documented with LZV.
- Recurrent HZ following immunization of individuals with a history of HZ prior to immunization, noting the area of recurrence.
- Recurrent HZO following immunization of a person who has had a previous episode of HZO. If available, a vitreous fluid specimen should be sent to a laboratory with a request to determine whether the virus is the vaccine strain or wild type virus.
For definitions of serious and unexpected adverse events, refer to Adverse Events Following Immunization in Part 2.
For more information refer to Reporting Adverse Events Following Immunization in Canada.
Reasons To Get The Shingles Vaccine
Once a person develops chickenpox after contracting the varicella-zoster virus, the virus never leaves the body. It remains dormant in the nerve roots and can reappear as shingles later in life.
The primary symptom of shingles is a painful rash on one side of the body, most often on the torso or face. People initially have pain or a burning sensation on the skin without a rash, and then painful blisters develop. The rash lasts approximately seven to 10 days and fully clears within two to four weeks.
The likelihood of developing shingles increases dramatically after age 50. Therefore, the Centers for Disease Control and Prevention recommends that all adults age 50 and over receive two doses of Shingrix to prevent shingles. The vaccine is recommended even if a person is unsure if they have ever had chickenpox.
People with weakened immune systems are at higher risk for shingles. Therefore, the Food and Drug Administration also recently approved Shingrix vaccination for adults age 18 and older who are at risk for shingles due to immunodeficiency or immunosuppression caused by an underlying disease or medication.
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I Got The Shingles Shot And Still Got Shingles How Come
Reader Question 741 votes
A
Its not really surprising that you got shingles after being vaccinated. No vaccine is 100 percent effective and whilechildhood vaccinations get close, the shingles vaccine only cuts the risk of shingles by half for people who receive it at age 60 or older. The Centers for Disease Control and Prevention recommends a single dose for those 60 or older, though the vaccine is approved for use starting at age 50.
Even though the vaccine is not always effective, it still protects a lot of people, since nearly one in three adults develops shingles during their lifetime. And if you do get shingles, you may have a milder episode because you were vaccinated. A large clinical trial found that the vaccine reduces the risk of having very severe, long-lasting pain, a syndrome called postherpetic neuralgia.
Its these extreme, prolonged painful episodes that the vaccine works better at preventing, said Dr. Rafael Harpaz, a medical epidemiologist in the division of viral diseases at the C.D.C.What would motivate me to run out and get the vaccine, he said, would be to protect myself from being that rare person who gets 10 years of life-shattering pain.
The vaccine may be most effective at younger ages. If you get it in your 60s, it reduces cases by nearly two thirds, or 64 percent it reduces risk by 41 percent if you are in your 70s when vaccinated and by 18 percent if you are in your 80s.
Do you have a health question? Submit your question to Ask Well.
What Questions Should I Ask My Healthcare Provider
Its normal to have questions before you get a vaccine. Some common questions you may want to discuss with your healthcare provider include:
- When should I get the shingles vaccine?
- What side effects should I expect?
- How does the shingles vaccine work?
- When should I schedule each dose of the shingles vaccine?
- How effective is the shingles vaccine?
- Is there any reason I shouldnt get the shingles vaccine?
- What could happen if I dont get the shingles vaccine?
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How Can I Prevent Getting Shingles
Prevent your children from getting shingles later in life by getting them immunized with the chickenpox vaccine. As an adult the best way to not get shingles is to get the shingles vaccine. The shingles vaccine is safe. It is much safer to get the vaccine than to get the disease. When you get immunized with the shingles vaccine you help protect others from chicken pox.
People with shingles can prevent spreading the virus by covering their rash, not touching or scratching the rash and washing their hands often.
Persons With Chronic Diseases
Autoimmune disease
Although definitive data are lacking, individuals with autoimmune disease not being treated with immunosuppressive drugs are not considered significantly immunocompromised. Individuals 50 years of age without contraindications should receive RZV.
For more information, refer to Immunization of Immunocompromised Persons, and Immunization of Persons with Chronic Diseases in Part 3.
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Who Should Get The Shingles Vaccine
The CDC recommends all healthy adults ages 50 years and older get two doses of the shingles vaccine to prevent shingles and problems that can develop after youve had the disease. The two doses should be separated by two to six months. You should get the shingles vaccine even if you:
- Have had shingles: If youve had shingles in the past, you should get the shingles vaccine to help prevent getting the disease again. You should wait until the shingles rash is gone before getting the vaccine.
- Arent sure if youve had chickenpox: Studies show more than 99% of Americans ages 40 and older have had chickenpox at some point in their lives. You should get the shingles vaccine whether or not you remember having chickenpox because theyre caused by the same virus.
- Received the old shingles vaccine : Before November 18, 2020, people were vaccinated with a shingles vaccine called Zostavax. You cant get Zostavax in the United States anymore. If you were vaccinated with Zostavax, you should get vaccinated with the new shingles vaccine, Shingrix.
Considerations For Patients Who Previously Received Zostavax
Studies have not examined the safety and immunogenicity of Shingrix administered less than 5 years following Zostavax vaccination. However, there are no data or theoretical concerns to indicate that Shingrix would be less safe or less effective when given at an interval shorter than 5 years following Zostavax. Since the risk of herpes zoster increases with age, providers should weigh a patients risk of herpes zoster with the age-specific protection expected from Zostavax to determine when to vaccinate with Shingrix.
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What Everyone Should Know About The Shingles Vaccine
Shingles vaccination is the only way to protect against shingles and postherpetic neuralgia , the most common complication from shingles.
CDC recommends that adults 50 years and older get two doses of the shingles vaccine called Shingrix to prevent shingles and the complications from the disease. Adults 19 years and older who have weakened immune systems because of disease or therapy should also get two doses of Shingrix, as they have a higher risk of getting shingles and related complications.
Your doctor or pharmacist can give you Shingrix as a shot in your upper arm.
Shingrix provides strong protection against shingles and PHN. In adults 50 years and older who have healthy immune systems, Shingrix is more than 90% effective at preventing shingles and PHN. Immunity stays strong for at least the first 7 years after vaccination. In adults with weakened immune systems, studies show that Shingrix is 68%-91% effective in preventing shingles, depending on the condition that affects the immune system.