Monday, September 25, 2023

How Long Does Shingrix Vaccine Last

What If I Wait Too Long To Take The Second Shingrix Dose

How long does SHINGRIX, a shingles vaccine, last?

The Centers for Disease Control and Prevention state that if more than 6 months have passed since you received your first dose, you should get the second dose as soon as possible. You dont have to start the doses all over again.

Also, if you get the second dose within 4 weeks after the first dose, it should not be counted. You should get your follow-up dose at least 1 to 2 months after the first dose, per your doctors recommendation.

What Happens If You Get The Shingles Vaccine And You Never Had Chickenpox

If youve never had chicken pox, no. If you did not get chicken pox as a child, dont get either vaccinations, it is likely that you are immune to the disease. Its very rare to give an adult the vaccine for chicken pox. Adults do not do well with childhood vaccinations because they can end up with complications.

Is Shingrix or Zostavax better? Shingrix is more effective than Zostavax. Shingrix is 97% effective at preventing shingles in adults aged 50 to 69 years old whereas Zostavax is only 70% effective at preventing shingles in the same age group.

The Problem With Medical Records Tracking Vaccine Schedules

Another obstacle is the fact that it can be difficult for family physicians to know exactly what vaccinations a patient has received. Unlike pediatric patients, who typically have accessible records of their vaccination schedule, it can be trickier for adults.

For adults, it becomes quite challenging, especially when they switch providers, because often times you have to track down records to find out if theyve been vaccinated, said Jain.

She said it can be complicated to try and decipher which vaccines patients have received and which ones they should get without clear records.

For adults over the age of 65, you want to find out if theyve gotten the two pneumonia vaccinations that are recommended, so it becomes a challenge to find out if theyve gotten both, or just one, she said.

Same thing goes now for the shingles vaccination. Youre kind of tracking down records, and when you dont have them, you have to make a clinical judgment.

Despite these challenges, Jain says the fact that Shingrix is a newly minted vaccination may make things a bit more straightforward.

The nice thing about Shingrix is that its so new, most patients have not gotten it, she said. Even if theyve had Zostavax, its recommended that they get Shingrix in addition to it, so thats a little bit less of a challenge with a new vaccination.

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Is The Shingles Vaccine Safe

As with any vaccine, its possible to have some side effects after receiving it. In clinical studies, the side effects linked to this vaccine usually lasted only 2 to 3 days, and the most common ones were:

  • Pain and redness at the injection site

  • Muscle pain

  • Fatigue

  • Headache

Most people report at least some arm pain after the injection. Some people reported that their side effects kept them from doing their usual daily activities. For this reason, its a good idea to plan to not do anything right after receiving your injection, just in case.

Severe allergic reaction to this vaccine is very rare. Symptoms of such a reaction include:

  • Hives

In clinical studies, there was no significant difference in efficacy over 4 years after vaccination. This suggests that if there is a decline in immunity, it does not happen quickly. Data beyond 4 years is not yet available.

Right now, its unclear if people will need an additional vaccine booster years later. Experts continue to research how long the vaccines efficacy lasts.

The vaccine is approved for adults aged 50 years and over. There is no best age, but theres no reason to wait once youre eligible.

Yes. Protection from the old vaccine wanes over time. Its recommended that you get Shingrix even if you received Zostavax in the past.

Shingrix And Other Medications

How Long Do The Effects Of The Shingles Vaccine Shingrix Last?

Below are medications that can interact with Shingrix. These are not all the drugs that may interact with Shingrix.

Before taking Shingrix, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Immunosuppressive drugs such as prednisone

Taking Shingrix with drugs that suppress your immune system can cause problems with the way your body responds to Shingrix. Examples of immunosuppressive medications include:

  • corticosteroids, such as:

Here are answers to some frequently asked questions about Shingrix.

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Itchy Skin Near The Injection Site

Itchy skin, also called pruritus, can potentially occur near the injection site after receiving Shingrix. Itching, swelling, and redness arent usually a huge cause for concern, as they often occur together as a localized reaction.

Applying Benadryl gel or hydrocortisone cream around the injection area can help reduce itchy, swollen, or red skin. If the itching worsens or spreads away from the injection site, get in touch with your doctor.

Who Should Get Shingrix

Healthy adults 50 years and older should get two doses of Shingrix, separated by 2 to 6 months. You should get Shingrix even if in the past you

  • had shingles
  • are not sure if you had chickenpox

There is no maximum age for getting Shingrix.

If you had shingles in the past, you can get Shingrix to help prevent future occurrences of the disease. There is no specific length of time that you need to wait after having shingles before you can receive Shingrix, but generally you should make sure the shingles rash has gone away before getting vaccinated.

You can get Shingrix whether or not you remember having had chickenpox in the past. Studies show that more than 99% of Americans 40 years and older have had chickenpox, even if they dont remember having the disease. Chickenpox and shingles are related because they are caused by the same virus . After a person recovers from chickenpox, the virus stays dormant in the body. It can reactivate years later and cause shingles.

Shingrix is available in doctors offices and pharmacies.

If you have questions about Shingrix, talk with your healthcare provider.

* A shingles vaccine called Zostavax is no longer available for use in the United States, as of November 18, 2020. If you had Zostavax in the past, you should still get Shingrix. Talk to your healthcare provider to determine the best time to get Shingrix.

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Can It Cause Side Effects

Like every vaccine, Shingrix has the potential for side effects, although so far, none seem particularly worrisome. The new shingles vaccine does appear to be more likely to cause pain during injection and at the site of injection for up to three days afterward than Zostavax does.

In clinical trials, the side effects also included injection site redness and swelling, muscle pain, and immune system responses such as headache, shivering, fever, and upset stomach. Most, according to GlaxoSmithKline, its manufacturer, lasted less than three days.

Though Shingrix was tested on some 16,600 adults in clinical trials, its real-world use has been limited. The company will be conducting additional safety and efficacy studies over the next few years, and the CDC will be monitoring any adverse events that are reported.

As with any drug thats approved on the basis of studies in only thousands, in contrast to millions after approval, strict post-marketing surveillance studies have to be agreed upon, with severe penalties for irregularities, says CRs Lipman.

Why Are Shingles So Painful

Long wait for shingles vaccine due to national shortage

Postherpetic neuralgia occurs if your nerve fibers are damaged during an outbreak of shingles. Damaged fibers cant send messages from your skin to your brain as they normally do. Instead, the messages become confused and exaggerated, causing chronic, often excruciating pain that can last months or even years.

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Dosage For Shingles Prevention

Shingrix is given as two 0.5-mL injections in your upper arm. Youll receive two doses of this vaccine.

Over time, some vaccines protection begins to fade, so may you need booster doses. They help keep the vaccine working. But you dont need a booster dose after getting the two doses of Shingrix.

Shingrix dosing schedule for people ages 50 years and older

For people ages 50 years and older taking Shingrix, the second dose is given 2 to 6 months after the first dose.

Shingrix dosing schedule for people ages 18 years and older with an increased risk of shingles

For people ages 18 years and older with an increased risk of shingles who are taking Shingrix, the second dose may be given 1 to 2 months after the first dose.

Who Should Get Vaccinated

Shingrix is approved for adults age 50 and older. Zostavax is no longer available for use in the United States as of November 18, 2020. You should get Shingrix even if in the past you had shingles, have received Zostavax, or are not sure if you had chicken pox. There is no maximum age for getting Shingrix.3

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What Is Shingrix The New Shingles Vaccine

Shingrix, approved by the U.S. Food and Drug Administration in late 2017, is more likely to cause short-term side effects than either Zostavax or other vaccines for adults, said Dr. Kathleen Dooling, a medical officer in the division of viral diseases at the Centers for Disease Control and Prevention.

One of the important things is to go into this vaccination knowing that youll probably have some side effects after and be prepared for those, Dooling told TODAY.

The advice weve been giving people is that if you plan to get the vaccine, in the day or two afterwards, dont plan any big, strenuous activities. For example, dont plan a big gardening project… dont plan your big golf game for that period.

Pain At Injection Site

Everything You Need to Know About the Shingles Vaccines

Pain at the injection site is a common side effect of many vaccines, including Shingrix. This pain is generally mild but can feel like anything from slight discomfort to deep bruising. In some cases, injection site pain can be severe enough to limit arm movement.

To ease this discomfort, you can apply cold packs to the affected area for 20 minutes at a time.

If these arent effective, over-the-counter pain remedies may help. However, if you have injection site pain that is severe or lasts longer than 2 to 3 days, follow up with your doctor.

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Coverage And Cost Comparison Of Shingrix Vs Zostavax

For adults aged 50 years and older, only plans with Medicare Part D coverage will cover the Shingrix vaccine. However, there may still be a copay even with Medicare Part D coverage. The average cash price for one Shingrix dose is $167, though you may be able to use a prescription discount card to lower this cost. Check with your local pharmacy to see if you can use a Shingrix SingleCare card.

Like Shingrix, Zostavax is primarily covered by Medicare Part D plans or Medicare Advantage plans with Medicare Part D coverage. The copay for Zostavax with insurance can vary. With an average cash price of $278, Zostavax can be expensive with or without insurance. Using a prescription discount card for Zostavax may be able to reduce this cost.

*

*not reportedFrequency is not based on data from a head-to-head trial. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more.Source: DailyMed , DailyMed

Why A New Shingles Vaccine

Did we need a new shingles vaccine? To answer that question, it helps to have a bit of background on this infection.

Shingles, which is also called herpes zoster, occurs when the chickenpox virus , which is dormant in those whove had the illness, reawakens later in life. Almost all adults older than 40 carry the chickenpox virusand the older we get, the more the risk of getting shingles climbs. According to the CDC, the infection strikes about 1 million people in the U.S. each year and nearly one in three adults will experience a bout of shingles in their lifetime.

The two to four weeks of shingles, marked by symptoms such as a blistery and painful rash on one side of the body, can be difficult enough. But about one in five people with shingles go on to develop postherpetic neuralgia, or PHN, which is nerve pain that can linger for months or even years.

Since 2006, weve had Zostavaxapproved for those between 50 and 59 but recommended by the CDC for adults 60 and olderas the sole bulwark against shingles. Zostavax offers 70 percent protection against shingles for people between 50 and 59 but only 18 percent in people 80 and older, according to the Pink Sheet, which reports on the pharmaceutical industry.

When all ages are taken into consideration, Zostavax cuts the chance of shingles by only 51 percent and the risk of PHN by 67 percent.

Shingles is a big problem with immunocompromised people, Schaffner says.

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More Common Side Effects

The more common side effects of Shingrix can include:

  • pain, redness, and swelling at site of injection*
  • headache*
  • dizziness or fainting
  • flu-like symptoms, including fever, shivering, and tiredness

Most of these side effects may go away within a few days or a couple of weeks. If theyre more severe or dont go away, talk to your doctor or pharmacist.

* For more information about this side effect, see Side effect details below.

Why Is It Important To Receive A Vaccination Against Shingles

New shingles vaccine is 90 percent effective, doctors say

About 33% of adults in the U.S. will develop shingles at some point in their lives. Shingles can cause painful blisters, a rash, chills, and fever, among other symptoms. Many people who have shingles later develop PHN, which can cause long-lasting pain that is difficult to treat.

Getting the Shingrix vaccine can help individuals avoid shingles and PHN and help prevent shingles from spreading to vulnerable people.

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Im Living With Hiv Is It Safe For Me To Get Shingrix

The Centers for Disease Control and Prevention hasnt made a recommendation about the use of Shingrix in people living with HIV.

However, one study looked at healthy adults ages 18 and older who were living with HIV and had an HIV dosing schedule that was customized to their needs. These people received the Shingrix vaccine, and the study results did not report any safety issues.

If youre living with HIV, talk with your doctor about the risks and benefits of getting Shingrix.

Doctors Worry Shingrix Side Effects Will Put Patients Off Their Second Dose

The CDC has urged people 50 and older to get GlaxoSmithKline’s new shingles vaccine to protect against a notoriously painful condition. But amid the company’s important launch, some doctors are worried patients won’t return for their second dose if they experience side effects.

Speaking with the U.S. News & World Report, geriatrician Arthur Hayward, M.D., said he heard concerns at a recent medical meeting that some patients will hesitate to return if they experience side effects.

According to Shingrix’s FDA label, 78% of vaccine recipients experienced pain at the injection site in clinical tests. Thirty-eight percent experienced redness and 25.9% experienced swelling. Other adverse reactions include muscle pain in 44.7% of recipients, fatigue in 44.5% of recipients, and headache in 37.7% of recipients, according to the FDA. A smaller number of recipients experienced shivering, fever and gastrointestinal symptoms.

A CDC official told the publication that 1 in 6 recipients had side effects severe enough to keep them from their normal activities.

But the side effects were typically mild to moderate and lasted two to three days, according to the FDA, while the vaccine provides strong protection against a condition that can cause pain for weeks. And, in some instances, shingles can lead to postherpetic neuralgia, or longer-term nerve pain that can persist for years.

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Who Should Not Get Shingrix

You should not get Shingrix if you:

  • have ever had a severe allergic reaction to any component of the vaccine or after a dose of Shingrix
  • tested negative for immunity to varicella zoster virus. If you test negative, you should get chickenpox vaccine.
  • currently have shingles
  • currently are pregnant or breastfeeding. Women who are pregnant or breastfeeding should wait to get Shingrix.

If you have a minor acute illness, such as a cold, you may get Shingrix. But if you have a moderate or severe acute illness, you should usually wait until you recover before getting the vaccine. This includes anyone with a temperature of 101.3°F or higher.

The side effects of the Shingrix are temporary, and usually last 2 to 3 days. While you may experience pain for a few days after getting Shingrix, the pain will be less severe than having shingles and the complications from the disease.

How Are Cvs Pharmacy And Minuteclinic Different

Shingles and the new vaccine

At Pharmacy, vaccinations for adolescents through seniors are administered by a certified immunizing pharmacist. Age and state restrictions apply. No appointment necessary.

At MinuteClinic, vaccinations for children through seniors are administered by a medical provider. View wait times and schedule a visit online, or walkâin anytime.

CVS Pharmacy and MinuteClinic also at Target

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Shingrix For Prevention Of Shingles

Shingrix is a vaccine thats used to prevent shingles . Its approved for use in people:

  • ages 50 years and older
  • ages 18 years and older who have an increased risk of shingles

People with an increased risk of shingles include those with a weakened immune system, such as people with HIV.

Shingrix is not meant for use in preventing chickenpox .

Effectiveness for prevention of shingles

Shingrix has been found to be effective in helping to prevent shingles. For details on how the drug performed in clinical studies, see Shingrixs

state that Shingrix is the preferred vaccine for shingles. They recommend it for:

  • all adults ages 50 years and older
  • adults ages 18 to 50 years with a weakened immune system

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