When To Get Vaccinations Against Bacterial Causes Of Meningitis
Meningitis is a disease thats defined by inflammation in membranes called meninges near your brain and spinal cord. It can have several different causes including viruses, bacteria, fungi, and some chemicals.
Different vaccines can protect you from the different causes of meningitis. Each has its own schedule for when you should receive it. Youll first get some of these vaccinations as an infant and others as a teenager or even as an adult. Many require boosters at various points throughout your life particularly if youre in a high-risk category for getting meningitis.
In general, vaccines are most helpful for protecting against bacterial meningitis, which is less common but more severe than viral meningitis.
Meningococcal vaccines protect against the meningitis-causing bacteria N. meningitidis. Two vaccines are currently approved for use in the U.S. Theyre called the MenACWY vaccine and the MenB vaccine.
The MenACWY vaccine is recommended for all young adults around the age of 11 or 12 years old plus a booster shot at 16 years. Another meningococcal vaccine called MenB is recommended between the ages of 16 to 18.
A good question to ask is: how long does the meningitis vaccine last? Even though both meningococcal vaccines produce an immune response, they lose effectiveness over time.
Healthy adults wont require another dose of this vaccine. But you should talk to your doctor about getting another pneumococcal vaccine if youre 65 years or older.
Immunisation Against Pneumococcal Disease For Babies And Children
The immunisation schedule for babies involves a course of a primary vaccine that reduces the risk of infection with 13 strains of pneumococcal bacteria.
A second type of vaccine that reduces the risk of infection with 23 strains of pneumococcal bacteria is given as a booster dose to children from four years of age if they:
- have a medical condition putting them at high risk of pneumococcal disease, or
- were born prematurely before 28 weeks gestation.
Protection for babies and children against pneumococcal disease is available under the National Immunisation Program Schedule. In Victoria, immunisation against pneumococcal disease is free of charge for:
What Is Pneumococcal Disease
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae or pneumococcus. People can be infected with the bacteria, or they can carry it in their throat, and not be ill. Those carriers can still spread it, primarily in droplets from their nose or mouth when they breathe, cough, or sneeze.
Depending on what organ or part of the body is infected, pneumococcal disease will cause any of several serious illnesses, including:
- Bacterial meningitis, an infection of the covering of the brain and spinal cord that can lead to confusion, coma, and death as well as other physical effects, such as blindness or paralysis
- Pneumonia, an infection of the lungs that creates cough, fever, and difficulty breathing
- Otitis media, a middle ear infection that can cause pain, swelling, sleeplessness, fever, and irritability
- Bacteremia, a dangerous infection of the blood stream
- Sinus infections
There are more than 6,000 deaths each year in the U.S. as a result of pneumococcal disease. More than half of those deaths are in adults who, according to CDC recommendations, should have been vaccinated.
In children under age 5, infection with the pneumococcus bacteria results in approximately 480 cases of meningitis and 4,000 cases of bacteremia or other invasive infection per year. A major problem in very young children is that the classic symptoms of meningitis and pneumonia are often not present, making the disease hard to recognize.
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Are Both Pneumococcal Vaccines Safe
Both vaccines are safe. As with any medicine there is always the possibility of a serious problem, such as an allergic reaction. But with PCV and PPSV , the risk of serious harm or death is extremely small.
In studies involving nearly 60,000 doses of the PCV vaccine, there have been no moderate or severe reactions. The mild side effects included:
- Redness, tenderness, or swelling where the shot is given in about one out of every four infants
- Fever higher than 100.4 F in about one out of every three infants
- Fever higher than 102.2 F in about one out of every 50 children
- Occasional incidence of fussiness, drowsiness, or loss of appetite
About one out of every two adults who receive the PPSV vaccine experiences redness or pain where the shot is given. Less than 1% have a more severe reaction, such as a fever or muscle aches.
Interchangeability Of 10vpcv And 13vpcv
There are no specific data on the interchangeability of 10vPCV and 13vPCV. It is preferable to complete a primary course of pneumococcal conjugate vaccine with the same formulation. However, if a child started their vaccination course with 10vPCV , it is acceptable to complete the course with 13vPCV
The only absolute contraindications to pneumococcal vaccines are:
- anaphylaxis after a previous dose of any pneumococcal vaccine
- anaphylaxis after any component of a pneumococcal vaccine
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What Is A Pneumococcal Vaccine
A pneumococcal vaccine is an injection that can prevent pneumococcal disease. A pneumococcal disease is any illness that is caused by pneumococcal bacteria, including pneumonia. In fact, the most common cause of pneumonia is pneumococcal bacteria. This type of bacteria can also cause ear infections, sinus infections, and meningitis.
Adults age 65 or older are amongst the highest risk groups for getting pneumococcal disease.
To prevent pneumococcal disease, there are two types of pneumococcal vaccines: the pneumococcal polysaccharide vaccine and the pneumococcal conjugate vaccine .
Who Needs To Get Vaccinated For Meningitis
Its especially important for you to keep all of your meningitis vaccinations up-to-date if you fall into a high-risk category for getting the disease. High-risk categories include:
- Certain Ages. Infants less than one-year-old and young adults between the ages of 16 and 21 are the most likely to develop meningitis. Its most important to have all boosters and available vaccinations at these ages.
- Crowded Settings. Large group settings like college campuses are where outbreaks of meningitis are the most common. Get your vaccines up-to-date before entering into these settings for extended periods of time.
- Certain underlying conditions. Some underlying medical conditions can increase your chance of getting meningitis. These include HIV and other conditions that weaken your immune system. Not having a spleen also places you at higher risk.
- Work that involves meningitis-causing agents. Microbiologists and any other researchers that regularly come into contact with the bacteria and viruses that cause meningitis are consistently at risk.
- Travel to certain areas. Some areas in the world like sub-Saharan Africa have higher rates of meningitis and the pathogens that cause it. Check with your doctor before traveling to new parts of the world.
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Who Should Not Get The Pneumococcal Vaccine Or Should Wait To Get It
- You should not get the vaccine if you have had an allergic reaction to it or to a vaccine for diphtheria, such as DTaP, Tdap, or Td. Tell your healthcare provider if you had an allergic reaction to any other vaccine. Also tell your provider if you have any severe allergies.
- You should wait to get the vaccine if you are sick or have a fever.
- You may need to wait to get the vaccine if you are a pregnant woman. If possible, get the vaccine before you become pregnant. Talk to your healthcare provider about the risks of this vaccine. Your provider can tell you if you are at high risk for pneumococcal infection and when to get the vaccine if you are already pregnant.
Are The Pneumonia Vaccines Safe
Yes, pneumonia vaccines are safe. Like all vaccines, they go through rigorous scientific testing and review. Although both pneumococcal vaccines can cause mild side effects, severe reactions to the vaccines are rare. In one study of adults over age 70 who received the PCV13 and PPSV23 vaccines, there was only one adverse event that was related to the vaccine.
Allergic reactions to vaccines are rare, but they can occur and may be serious. If you have had an allergic reaction to one of the ingredients in the pneumococcal vaccines or to a prior dose of a pneumococcal vaccine, you should not get vaccinated without talking to your healthcare provider first.
If you have questions about whether the pneumonia vaccines are safe for you, discuss this with your healthcare provider. You can also find information about pneumococcal vaccine safety here.
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Medical Conditions Resulting In High Risk Of Ipd
Table 1: Medical Conditions Resulting in High risk of IPD
IPD is more common in the winter and spring in temperate climates.
Spectrum of clinical illness
Although asymptomatic upper respiratory tract colonization is common, infection with S. pneumoniae may result in severe disease. IPD is a severe form of infection that occurs when S. pneumoniae invades normally sterile sites, such as the bloodstream or central nervous system. Bacteremia and meningitis are the most common manifestations of IPD in children 2 years of age and younger. Bacteremic pneumococcal pneumonia is the most common presentation among adults and is a common complication following influenza. The case fatality rate of bacteremic pneumococcal pneumonia is 5% to 7% and is higher among elderly persons. Bacterial spread within the respiratory tract may result in AOM, sinusitis or recurrent bronchitis.
Worldwide, pneumococcal disease is a major cause of morbidity and mortality. The World Health Organization estimates that almost 500,000 deaths among children aged less than 5 years are attributable to pneumococcal disease each year. In Canada, IPD is most common among the very young and adults over 65 years of age.
Immunisation Against Pneumococcal Disease For Adults
Adult immunisation against pneumococcal disease is available free of charge under the National Immunisation Program Schedule for:
- any person with certain serious medical risk conditions
- all Aboriginal and Torres Strait Islander people aged 50 years or older
- people aged from 70 years.
Some medical risk conditions for which it is recommended to receive pneumococcal immunisation do not qualify for free immunisation under the National Immunisation Program. Speak to your doctor or immunisation provider for further information about the vaccine and its cost.
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Children At High Risk Of Ipd
Infants at high risk of IPD due to an underlying medical condition should receive Pneu-C-13 vaccine in a 4 dose schedule at 2 months, 4 months and 6 months followed by a dose at 12 to 15 months of age. Table 3 summarizes the recommended schedules for Pneu-C-13 vaccine for infants and children at high risk of IPD due to an underlying medical condition by pneumococcal conjugate vaccination history.
In addition to Pneu-C-13 vaccine, children at high risk of IPD due to an underlying medical condition should receive 1 dose of Pneu-P-23 vaccine at 24 months of age, at least 8 weeks after Pneu-C-13 vaccine. If an older child or adolescent at high risk of IPD due to an underlying medical condition has not previously received Pneu-P-23 vaccine, 1 dose of Pneu-P-23 vaccine should be administered, at least 8 weeks after Pneu-C-13 vaccine. Children and adolescents at highest risk of IPD should receive 1 booster dose of Pneu-P-23 vaccine refer to Booster doses and re-immunization. Refer to Immunocompromised persons for information about immunization of HSCT recipients.
Table 3: Recommended Schedules for Pneu-C-13 Vaccine for Children 2 months to less than 18 years of age, by Pneumococcal Conjugate Vaccination History
|Age at presentation for immunization||Number of doses of Pneu-C-7, Pneu-C-10 or Pneu-C-13 previously received|
Concurrent Administration Of Vaccines
Pneumococcal vaccines may be administered concomitantly with other vaccines, with the exception of a different formulation of pneumococcal vaccine . There should be at least an 8 week interval between a dose of pneumococcal conjugate vaccine and a subsequent dose of Pneu-P-23 vaccine, and at least a 1 year interval between a dose of Pneu-P-23 vaccine and a subsequent dose of pneumococcal conjugate vaccine refer to Immunocompromised persons for information regarding administration of pneumococcal vaccines to HSCT recipients. Different injection sites and separate needles and syringes must be used for concurrent parenteral injections. Refer to Timing of Vaccine Administration in Part 1 for additional information about concurrent administration of vaccines.
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How Are Cvs Pharmacy And Minuteclinic Different
At the pharmacy, vaccinations for adolescents through seniors are administered by a certified immunizationâtrained pharmacist. Age and state restrictions apply. No appointment necessary.
At MinuteClinic, vaccinations for children all the way through seniors are administered by a nurse practicioner or a physician associate.* No appointment necessary.
What Are The Possible Side Effects Of Pcv And Ppsv Vaccines
Kids may have redness, tenderness, or swelling where the shot was given. A child also might have a fever after getting the shot. There is a very small chance of an allergic reaction with any vaccine.
The pneumococcal vaccines contain only a small piece of the germ and so cannot cause pneumococcal disease.
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What Is The Pneumococcal Vaccine
The pneumococcal vaccine is an injection given to protect you from pneumococcal disease. Pneumococcal disease develops from an infection caused by pneumococcal bacteria. The infection may cause pneumonia or an ear infection. Pneumococcal disease is spread from person to person through coughing and sneezing. The vaccine comes in 2 forms, called pneumococcal conjugate vaccine and pneumococcal polysaccharide vaccine .
Managing Fever After Immunisation
Common side effects following immunisation are usually mild and temporary . Specific treatment is not usually required.
There are a number of treatment options that can reduce the side effects of the vaccine including:
- giving extra fluids to drink and not overdressing if there is a fever
- although routine use of paracetamol after vaccination is not recommended, if fever is present, paracetamol can be given check the label for the correct dose or speak with your pharmacist, .
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Global Epidemiology Since The Introduction Of Pneumococcal Conjugate Vaccines
Direct impact of PCV programmes on IPD in children
Reductions in IPD among target cohorts of children in high income countries have been similar for PCV10 and PCV7/13 in reported studies. Québec and Finland both used 2+1 schedules and observed 83 percent and 79 percent reductions in IPD in vaccine-eligible children, respectively. In England, using PCV7 then PCV13 in a 2+1 schedule, there was an estimated 5,000 fewer hospital admissions for bacteraemia, meningitis and pneumonia in children aged under 5 years over 12 years after the introduction of PCV7 and PCV13. The greatest reductions were seen in meningitis in children under 2 years age.
Direct impact of vaccination on non-invasive pneumococcal disease
The impact of pneumococcal conjugate vaccination on the large burden of noninvasive pneumococcal disease has been clearly demonstrated internationally in countries that have introduced these vaccines, particularly through reductions in childhood hospitalisations due to pneumonia. Other impacts, such as on acute otitis media, are less clear and more difficult to measure accurately. However, a systematic review found PCVs were associated with large reductions in risk of pneumococcal acute otitis media, but there was no evidence of benefit against allcause otitis media in high-risk children over 1 year of age or older children with a history of respiratory illness.
Concerns About Immunisation Side Effects
If the side effect following immunisation is unexpected, persistent or severe or if you are worried about yourself or your childs condition after a vaccination, see your doctor or immunisation nurse as soon as possible or go directly to a hospital. Immunisation side effects may be reported to SAEFVIC, the Victorian vaccine safety service.
It is also important to seek medical advice if you are unwell, as this may be due to other illness rather than because of the vaccination.
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What Are The Possible Side Effects Of Pneumococcal Immunisation
All medicines and vaccines can have side effects. Sometimes they are serious, most of the time theyre not.
For most people, the chance of having a serious side effect from a vaccine is much lower than the chance of serious harm if you caught the disease.
Talk to your doctor about possible side effects of pneumococcal vaccines, or if you or your child have symptoms after having a pneumococcal vaccine that worry you.
Common side effects of pneumococcal vaccines include:
- pain, redness and swelling where the needle went in
- reduced appetite
- body aches.
Who Should Have The Pneumococcal Vaccine
Anyone can get a pneumococcal infection. But some people are at higher risk of serious illness, so it’s recommended they’re given the pneumococcal vaccination on the NHS.
- adults aged 65 or over
- children and adults with certain long-term health conditions, such as a serious heart or kidney condition
Babies are offered 2 doses of pneumococcal vaccine, at 12 weeks and at 1 year of age.
People aged 65 and over only need a single pneumococcal vaccination. This vaccine is not given annually like the flu jab.
If you have a long-term health condition you may only need a single, one-off pneumococcal vaccination, or a vaccination every 5 years, depending on your underlying health problem.
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Acip Guidelines Aged 2
Any of the following conditions:
Chronic heart disease
Chronic lung disease
Diabetes mellitus Cerebrospinal fluid leak
Sickle cell disease and other hemoglobinopathies
Anatomic or functional asplenia
Chronic renal failure
Diseases associated with immunosuppressive drugs or radiation therapy, including malignant neoplasms, leukemias, lymphomas, and Hodgkin disease solid organ transplantation or congenital immunodeficiency
Dosage for high risk 2-5 years olds
- 1. Administer 1 dose of PCV13 if 3 doses of PCV were received previously
- 2. Administer 2 doses of PCV at least 8 weeks apart if fewer than 3 doses of PCV13 were received previously
- 3. Administer 1 supplemental dose of PCV13 if 4 doses of PCV7 or other age-appropriate complete PCV7 series was received previously
- 4. The minimum interval between doses of PCV is 8 wk
- 5. For children with no history of PPSV23 vaccination, administer PPSV23 at least 8 wk after the most recent dose of PCV13