What Is Pneumococcal Disease
Pneumococcal disease is an infection caused by the bacteria Streptococcus pneumoniae. This bacteria commonly shortened to pneumococcus is a common cause of pneumonia and other invasive diseases. An invasive disease is when a germ is in a part of the body thats usually germ-free.
Meningitis a serious infection that surrounds the brain and spinal cord can be caused by a variety of germs, including pneumococcus. Pneumococcus can also cause blood infections , sinus infections, and ear infections.
Pneumococcal vaccines are available to help protect against pneumococcal disease. More on this below.
Who Shouldnt Get Prevnar 20
People who have had a severe allergic reaction in the past to any of the vaccines ingredients including diphtheria protein should not receive Prevnar 20. People who are 17 years or younger also shouldnt receive this vaccine.
At this time, the FDA didnt place any other restrictions on who can receive Prevnar 20. If youre unsure if you should receive this vaccine, your healthcare provider can give you more information.
Pneumococcal Vaccination For The Diagnosis Of Immunodeficiency
From a young age, humans are exposed to pneumococcal serotypes, with colonisation of the nasopharyngeal tract seen in 40% or more of children . Therefore, even outside the context of vaccination, immunocompetent individuals should have detectable levels of total pneumococcal antibodies. If pneumococcal antibody levels are low or specific serotype levels are below the currently recommended protective level for IPD, then individuals should be immunised to assess their vaccine response and to afford these individuals protective antibody levels if they mount a good response. Currently, the threshold for protective serotype-specific antibody level is 0.35 g/mL for the PCV13 and it is expected that post-vaccination antibody levels should be > 0.35 ug/mL for at least 7 out of the 13 serotypes found in PCV13 . It should be stressed that the threshold value is a composite value for all vaccine-related serotypes however, in practice, thresholds are likely to vary with serotype and the concentration for protection against invasive and non-invasive disease and colonisation will also differ . The protective serotype-specific antibody level following PPV23 is considered to be 1.3 ug/mL .
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How Often Is The Pneumococcal Vaccine Given
Babies receive the pneumococcal vaccine as three separate injections, at 2 months, 4 months and 12-13 months.
People over-65 only need a single pneumococcal vaccination which will protect for life. It is not given annually like the flu jab.
People with a long term health condition may need just a single one-off pneumococcal vaccination or five-yearly vaccination depending on their underlying health problem.
Whats The Difference Between Pcv13 And Ppsv23
|helps protect you against 13 different strains of pneumococcal bacteria||helps protect you against 23 different strains of pneumococcal bacteria|
|usually given four separate times to children under two||generally given once to anyone over 64|
|generally given only once to adults older than 64 or adults older than 19 if they have an immune condition||given to anyone over 19 who regularly smokes nicotine products like cigarettes or cigars|
- Both vaccines help prevent pneumococcal complications like bacteremia and meningitis.
- Youll need more than one pneumonia shot during your lifetime. A 2016 study found that, if youre over 64, receiving both the PCV13 shot and the PPSV23 shot provide the best protection against all the strains of bacteria that cause pneumonia.
- Dont get the shots too close together. Youll need to wait about a year in between each shot.
- Check with your doctor to make sure youre not allergic to any of the ingredients used to make these vaccines before getting either shot.
- a vaccine made with diphtheria toxoid
- another version of the shot called PCV7
- any previous injections of a pneumonia shot
- are allergic to any ingredients in the shot
- have had severe allergies to a PPSV23 shot in the past
- are very sick
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How Does It Work
Prevnar 20 is a conjugate vaccine. This means that it contains pieces of sugar-like substances called polysaccharides that typically coat the bacteria but also hide it from our immune system. The vaccine uses only a certain portion of the bacteria not the bacteria itself so its unable to cause an infection.
This conjugate vaccine uses 20 slightly different polysaccharides that are specific to the 20 serotypes and attaches them to proteins that our immune systems can recognize. If the bacteria enters the body after the vaccination is administered, the immune system can recognize the polysaccharide molecule and release antibodies to fight the bacteria before it causes an infection.
What Are The Possible Side Effects Of Pcv And Ppsv Vaccines
Kids may have redness, tenderness, or swelling where the shot was given. A child also might have a fever after getting the shot. There is a very small chance of an allergic reaction with any vaccine.
The pneumococcal vaccines contain only a small piece of the germ and so cannot cause pneumococcal disease.
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Side Effects Of The Vaccines Against Pneumococcal Disease
Vaccines against pneumococcal disease are effective and safe, although all medications can have unwanted side effects.
Side effects from the vaccine are uncommon and usually mild, but may include:
- localised pain, redness and swelling at the injection site
- occasionally, an injection-site lump that may last many weeks
- low-grade temperature .
Persons New To Canada
Health care providers who see persons newly arrived in Canada should review the immunization status and update immunization for these individuals, as necessary. Review of pneumococcal vaccination status is particularly important for persons from areas of the world where sickle cell disease is present, as persons with sickle cell disease are at risk of serious pneumococcal infections. In many countries outside of Canada, pneumococcal conjugate vaccine is in limited use. Refer to Immunization of Persons New to Canada in Part 3 for additional information about vaccination of people who are new to Canada.
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Are You 65 Or Older Get Two Vaccinations Against Pneumonia
- By Gregory Curfman, MD, Assistant Professor of Medicine, Former Editor-in-Chief, Harvard Health Publishing
ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Please note the date each article was posted or last reviewed. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.
If you or a loved one is age 65 or older, getting vaccinated against pneumonia is a good idea so good that the Centers for Disease Control now recommends that everyone in this age group get vaccinated against pneumonia twice.
This new recommendation is based on findings from a large clinical trial called CAPiTA, which were published today in The New England Journal of Medicine.
Streptococcus pneumoniae, sometimes just called pneumococcus, is a common bacterium that can cause serious lung infections like pneumonia. It can also cause invasive infections of the bloodstream, the tissues covering the brain and spinal cord , and other organs and tissues. Older individuals are especially prone to being infected by Pneumococcus, and these infections are often deadly.
The dark spots are pneumonia-causing Streptococcus pneumoniae bacteria isolated from the blood of an infected person.
One caveat is that while PCV13 is effective in preventing pneumonia caused by S. pneumoniae, it does not prevent pneumonia caused by viruses or other bacteria.
What Is A Pneumococcal Vaccine
A pneumococcal vaccine is an injection that can prevent pneumococcal disease. A pneumococcal disease is any illness that is caused by pneumococcal bacteria, including pneumonia. In fact, the most common cause of pneumonia is pneumococcal bacteria. This type of bacteria can also cause ear infections, sinus infections, and meningitis.
Adults age 65 or older are amongst the highest risk groups for getting pneumococcal disease.
To prevent pneumococcal disease, there are two types of pneumococcal vaccines: the pneumococcal polysaccharide vaccine and the pneumococcal conjugate vaccine .
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Everything You Need To Know About The Pneumonia Vaccine
During the winter months, many people think that they have a nasty cold or flu, but it turns out to be pneumonia an illness that can be life threatening in certain people. A vaccine can help lower your chance of contracting pneumonia. While the pneumonia vaccine does not prevent all cases of pneumonia, it reduces the severity of the disease.
That is especially important for older adults and if you have certain medical conditions that put you at greater risk for complications.
Now is the time to talk to your doctor about your risks and if you need a vaccine to protect you against pneumonia.
Niharika Juwarkar, MD, Internal Medicine with Firelands Physician Group, answers your most frequently asked questions about pneumonia and the risks.
What is pneumonia?
Pneumonia is a respiratory lung infection that is often mistaken for the flu. Your lungs become filled with fluid or pus that results in inflammation. Symptoms are very similar to the flu, but pneumonia can last for weeks and result in very serious complications.
While pneumonia can be caused by bacteria, viruses or fungi, most cases are due to a specific bacteria called streptococcus pneumoniae, more commonly known as pneumococcal pneumonia. This form can be treated with antibiotics. Your doctor can test to see what form of pneumonia you have. Treatment depends on the type of pneumonia you have and the severity of your symptoms. But, the best defense is vaccination.
Who is most at risk for pneumonia?
How Often Do You Need To Get A Pneumonia Shot
Answer it5 to 10 years
Also to know is, how often do you have to get the Prevnar 13 shot?
CDC recommends 2 pneumococcal vaccines for all adults 65 years or older.
- You should receive a dose of PCV13 first, followed by a dose of PPSV23, at least 1 year later.
- If you already received any doses of PPSV23, get the dose of PCV13 at least 1 year after the most recent PPSV23 dose.
Who qualifies for a pneumococcal vaccine?
Who is eligible for the pneumonia vaccine?
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Know The Facts About The Pneumonia Vaccine
Just as with a flu shot, and now the COVID-19 vaccines, some people believe that getting a pneumococcal vaccine will cause them to come down with the disease or experience long-term side effects.
This is absolutely not true, Dr. Suri says.
Not only will the pneumococcal vaccine help reduce the risk of contracting certain types of bacterial pneumonia, it also guards against serious consequences resulting from the flu and severe infections, such as .
For young children, older adults, smokers and those with other risk factors, the vaccine is a healthy choice to make.
I cant see any reason to avoid this vaccine and every reason to get it, she says.
Persons With Chronic Diseases
Refer to Immunization of Persons with Chronic Diseases in Part 3 for additional information about vaccination of people with chronic diseases.
Asplenia or hyposplenia
Hyposplenic or asplenic individuals should receive Pneu-C-13 vaccine and Pneu-P-23 vaccine, followed by a booster dose of Pneu-P-23 vaccine. Refer to Table 3, Table 4 and Booster doses and re-immunization for additional information.
Chronic kidney disease and patients on dialysis
Individuals with chronic kidney disease should receive age appropriate pneumococcal vaccines. Children less than 18 years of age with chronic kidney failure or nephrotic syndrome, should receive Pneu-C-13 vaccine and Pneu-P-23 vaccine. Adults with chronic kidney failure should receive Pneu-P-23 vaccine. Adults with nephrotic syndrome should receive Pneu-C-13 and Pneu-P-23 vaccine. Due to the decreased immunogenicity and efficacy of Pneu-P-23 vaccine in children and adults with chronic kidney failure, 1 booster dose of Pneu-P-23 vaccine is recommended. Refer to Table 3, Table 4 and Booster doses and re-immunization for additional information.
Chronic lung disease, including asthma
Chronic heart disease
Chronic liver disease
Endocrine and metabolic diseases
Non-malignant hematologic disorders
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When Will Prevnar 20 Be Available
We dont know yet when Prevnar 20 will be available since a specific timeline hasnt been announced yet.
Healthcare providers reference the CDCs updated immunizations schedules complex diagrams that show when and how vaccines should be administered to help make sure appropriate vaccines are administered. Prevnar 20 is not yet incorporated into these schedules, so its difficult for healthcare providers to know who specifically should receive the vaccine at this time.
However, its likely that ACIP will recommend the vaccines use and add it to the immunization schedule after they meet in October 2021.
Who Should Get Immunised Against Pneumococcal Disease
Anyone who wants to protect themselves against pneumococcal disease can talk to their doctor about getting immunised.
Pneumococcal immunisation is recommended for:
- infants and children aged under 5 years
- non-Indigenous adults aged 70 years and over without medical risk conditions for pneumococcal disease
- Aboriginal and Torres Strait Islander children aged under 5 years living in Northern Territory, Queensland, South Australia and Western Australia
- Aboriginal and Torres Strait Islander adults aged 50 years and over without medical risk conditions for pneumococcal disease
- infants under 12 months diagnosed with certain medical risk conditions for pneumococcal disease
- people over 12 months with certain medical risk conditions for pneumococcal disease
There are two types of pneumococcal vaccine provided free under the National Immunisation Program for different age groups and circumstances:
Refer to the NIP schedule for vaccine dosage information. Your doctor or vaccination provider will advise if you or your child have a specified medical risk condition.
Refer to the pneumococcal recommendations in the Australian Immunisation Handbook for more information.
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Common And Local Adverse Events
Pneumococcal conjugate vaccine
Studies of Pneu-C-13 vaccine indicated that irritability decreased appetite increased or decreased sleep and pain, swelling and redness at the injection site after the toddler dose and in older children, are common side effects. Low grade fever occurred in 20% to 30% or more of vaccine recipients. In adults over 50 years of age, the most commonly reported side effects included pain at the injection site, fatigue, headache and new onset of myalgia, with fever above 38Â°C occurring in approximately 3% of vaccine recipients.
Pneumococcal polysaccharide vaccine
Reactions to Pneu-P-23 vaccine are usually mild. Soreness, redness and swelling at the injection site occur in 30% to 60% of vaccine recipients and more commonly follow SC administration than IM administration. Occasionally, low grade fever may occur. Re-immunization of healthy adults less than 2 years after the initial dose is associated with increased injection site and systemic reactions. Studies have suggested that re-vaccination after an interval of at least 4 years is not associated with an increased incidence of adverse side effects. However, severe injection site reactions, including reports of injection site cellulitis and peripheral edema in the injected extremity, have been documented rarely with Pneu-P-23 vaccine in post-marketing surveillance, even with the first dose. Multiple re-vaccinations are not recommended refer to Booster doses and re-immunization.
When Should Pneumococcal Vaccine Be Given
. Keeping this in view, when should I get pneumonia vaccine?
The pneumonia shot is especially recommended if you fall into one of these age groups: Younger than 2 years old: four shots 65 years old or older: two shots, which will last you the rest of your life.
Similarly, who should receive the pneumococcal vaccine? CDC recommends pneumococcal vaccination for all children younger than 2 years old and all adults 65 years or older. In certain situations, other children and adults should also get pneumococcal vaccines.
Secondly, how often is pneumococcal vaccine given?
People aged 65 and over only need a single pneumococcal vaccination. This vaccine is not given annually like the flu jab. People with a long-term health condition may need just a single one-off pneumococcal vaccination or vaccination every 5 years, depending on their underlying health problem.
Is pneumococcal vaccine necessary?
Available Pneumococcal VaccinesPCV13 protects against the 13 types of pneumococcal bacteria that cause the most severe illness among children and adults. It is recommended for routine use among children younger than 5 years of age and adults 65 years of age and older.
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When To Get The Vaccine
Thereâs no such thing as pneumonia season, like flu season. If you and your doctor decide that you need to have a pneumonia vaccine, you can get it done at any time of the year. If itâs flu season, you can even get a pneumonia vaccine at the same time that you get a flu vaccine, as long as you receive each shot in a different arm.
Adults At High Risk Of Ipd
Adults with immunocompromising conditions resulting in high risk of IPD, except HSCT, should receive 1 dose of Pneu-C-13 vaccine followed at least 8 weeks later by 1 dose of Pneu-P-23 vaccine, if not previously received. The dose of Pneu-C-13 vaccine should be administered at least 1 year after any previous dose of Pneu-P-23 vaccine. Refer to Immunocompromised persons for information about immunization of HSCT recipients.
Immunocompetent adults with conditions or lifestyle factors resulting in high risk of IPD should receive 1 dose of Pneu-P-23 vaccine, if not previously received. One dose of Pneu-P-23 vaccine is also recommended for all adults who are residents of long-term care facilities and should be considered for individuals who use illicit drugs.
Some experts also suggest a dose of Pneu-C-13 vaccine, followed by Pneu-P-23 vaccine, for immunocompetent adults with conditions resulting in high risk of IPD as this may theoretically improve antibody response and immunologic memory. However, Pneu-P-23 vaccine is the vaccine of choice for these individuals, and if only one vaccine can be provided, it should be Pneu-P-23 vaccine, because of the greater number of serotypes included in the vaccine.
Adults at highest risk of IPD should also receive 1 booster dose of Pneu-P-23 vaccine refer to Booster doses and re-immunization.
Table 4 – provides recommended schedules for adult immunization with pneumococcal vaccines.
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