Interchangeability Of 10vpcv And 13vpcv
There are no specific data on the interchangeability of 10vPCV and 13vPCV. It is preferable to complete a primary course of pneumococcal conjugate vaccine with the same formulation. However, if a child started their vaccination course with 10vPCV , it is acceptable to complete the course with 13vPCV
The only absolute contraindications to pneumococcal vaccines are:
- anaphylaxis after a previous dose of any pneumococcal vaccine
- anaphylaxis after any component of a pneumococcal vaccine
Are The Pneumonia Vaccines Safe
Yes, pneumonia vaccines are safe. Like all vaccines, they go through rigorous scientific testing and review. Although both pneumococcal vaccines can cause mild side effects, severe reactions to the vaccines are rare. In one study of adults over age 70 who received the PCV13 and PPSV23 vaccines, there was only one adverse event that was related to the vaccine.
Allergic reactions to vaccines are rare, but they can occur and may be serious. If you have had an allergic reaction to one of the ingredients in the pneumococcal vaccines or to a prior dose of a pneumococcal vaccine, you should not get vaccinated without talking to your healthcare provider first.
If you have questions about whether the pneumonia vaccines are safe for you, discuss this with your healthcare provider. You can also find information about pneumococcal vaccine safety here.
Is Pneumococcal Disease Dangerous
Yes. It can be. Pneumococcal disease is one of the most common causes of vaccine-preventable death in this country. Every year thousands of people need hospital treatment and more than 4,400 people die because of pneumococcal disease. Pneumococcal infection is the most common cause of bacterial pneumonia. It is also a leading cause of meningitis, blood infection and ear infection in children.
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Persons With Inadequate Immunization Records
Children and adults lacking adequate documentation of immunization should be considered unimmunized and should be started on an immunization schedule appropriate for their age and risk factors. Pneumococcal vaccines may be given, regardless of possible previous receipt of the vaccines, as adverse events associated with repeated immunization have not been demonstrated. Refer to Immunization of Persons with Inadequate Immunization Records in Part 3 for additional information about vaccination of people with inadequate immunization records.
Side Effects Of The Vaccines Against Pneumococcal Disease
Vaccines against pneumococcal disease are effective and safe, although all medications can have unwanted side effects.
Side effects from the vaccine are uncommon and usually mild, but may include:
- localised pain, redness and swelling at the injection site
- occasionally, an injection-site lump that may last many weeks
- low-grade temperature .
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How The Pneumococcal Vaccine Works
Both types of pneumococcal vaccine encourage your body to produce antibodies against pneumococcal bacteria.
Antibodies are proteins produced by the body to neutralise or destroy disease-carrying organisms and toxins.
They protect you from becoming ill if you’re infected with the bacteria.
More than 90 different strains of the pneumococcal bacterium have been identified, although most of these strains do not cause serious infections.
The childhood vaccine protects against 13 strains of the pneumococcal bacterium, while the adult vaccine protects against 23 strains.
How Is The Pneumococcal Vaccine Made
Like the Hib vaccine, the pneumococcal vaccine is made from the sugar coating of the bacteria. Antibodies directed against the pneumococcal polysaccharide protect the child without having to take the risk that their first encounter with natural pneumococcus will result in permanent disabilities or death.
Unfortunately, children less than 2 years old don’t develop very good immune responses to this polysaccharide alone. So the pneumococcal vaccine was made in a manner similar to the Hib vaccine . The pneumococcal polysaccharide is linked to a harmless protein. This version of the vaccine is referred to as the pneumococcal conjugate vaccine. Once linked, young children are able to make an immune response to the polysaccharide. The big difference between the pneumococcal vaccine and the Hib vaccine is the number of different types of polysaccharides that need to be included in the vaccine. Whereas, there is really only one strain of Hib that causes disease in children, there are about 90 different strains of pneumococcus. Fortunately, most of the serious disease in young children is caused by the 13 strains of pneumococcus contained in the vaccine.
The pneumococcal vaccine was found to be highly effective in preventing severe pneumococcal infection in a large trial of children injected with the vaccine. About 40,000 children were included in the initial trial of the vaccine. Since its licensure, the pneumococcal vaccine has been given to millions of children safely.
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Who Needs A Pneumococcal Vaccination
Anyone aged 65 years or over is eligible for the vaccine. GPs may, at their own discretion, provide immunisation to anyone aged under 65 with the following serious medical conditions:
- problems with the spleen, either because the spleen has been removed or doesnt work properly – for example sickle cell disorder and coeliac disease
- chronic lung disease, including chronic bronchitis or emphysema
- serious heart conditions
Which Pneumonia Vaccine Is Best
There is no best pneumonia vaccine. The two available pneumonia vaccines are different, and which one is best for you depends on how old you are and whether or not you have certain medical conditions.
The main difference between Prevnar 13 and Pneumovax 23 is the number of pneumococcus strains the vaccine protects against.
PCV13 contains polysaccharides from 13 types of pneumococcal bacteria and is mainly given to young children.
PPSV23 contains polysaccharides from 23 types of pneumococcal bacteria and is mainly given to older adults.
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What To Do If Your Child Is Unwell After Pneumococcal Vaccination
Most common side effects in babies and young children, such as swelling or redness at the injection site, usually go away within a couple of days and you do not need to do anything about them.
If your child develops a fever, keep them cool. Make sure they do not wear too many layers of clothes or blankets, and give them cool drinks.
You can also give them a dose of infant paracetamol or ibuprofen liquid according to the instructions on the bottle.
Read an NHS leaflet about the common side effects of vaccination that may occur in babies and children under the age of 5, and how to treat them.
When To Get The Vaccine
Thereâs no such thing as pneumonia season, like flu season. If you and your doctor decide that you need to have a pneumonia vaccine, you can get it done at any time of the year. If itâs flu season, you can even get a pneumonia vaccine at the same time that you get a flu vaccine, as long as you receive each shot in a different arm.
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The Flu Pneumonia And Inflammation Create A Deadly Threat
Pneumococcal pneumonia can follow other viral infections, particularly influenza, says William Schaffner, M.D., an infectious disease specialist at the Vanderbilt University School of Medicine. The biology behind it:The flu virus attaches to, and infects, the cells lining the mucous membranes in the back of the throat, nose and bronchial tubes. Normally, the cells eject infectious agents out of the body via the nose or mouth, or they’re simply swallowed. But when impaired by the flu, the cells lining these membranes allow the bacteria to slip down into the bronchial tubes and trigger a secondary infection, in the lungs. The infection inflames the air sacs in the lungs, causing them to fill with pus and fluid. That not only makes it hard to breathe but can allow bacteria to escape into the bloodstream, causing an infection called sepsis, an aggressive inflammatory response that can, ultimately, lead to organ failure.
Pneumococcal pneumonia, of course, is also likely be a complication of respiratory syncytial virus , a common and highly contagious winter lung infection, whichuncharacteristicallyspread this summer, and SARS-CoV-2, the virus that causes COVID-19. However, the pneumococcal vaccine wont shield you from pneumonia that results from either of them. As Schaffner puts it, Pneumonia from Covid is a different sort of pneumonia.
Groups At Risk Of Ipd
People who are immunocompromised and unable to mount an adequate immune response to pneumococcal capsular antigens have the highest risk of IPD.2,4,34 This includes people with asplenia.
Greater risk and/or severity of IPD
- excessive alcohol consumption
- certain non-immunocompromising chronic medical conditions2,34,42,43
Indigenous populations in developed countries, including Aboriginal and Torres Strait Islander people in Australia, have a disproportionately high burden of IPD
Young children and elderly people have the highest incidence of invasive pneumococcal disease .37,38,45 Disease burden is also disproportionately high in Aboriginal and Torres Strait Islander people.1,2
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Who Should Get Pneumococcal Conjugate Vaccine
- All infants and children younger than 2 years of age.
- Older children and adolescents:
- Healthy children 2 through 5 years of age who have not completed the PCV series
- Children 2 through 5 years of age with underlying medical conditions who have not completed the PCV series
- Healthy children 2 through 4 years of age who have received only PCV7
- Children 5 through 6 years of age with underlying medical conditions who have received only PCV7
- Children 6 through 18 years of age who have functional or anatomic asplenia HIV infection or other immunocompromising condition cochlear implant or cerebral spinal fluid leak
Ask your doctor if your child needs another dose of this vaccine.
Pneumococcal Infections After Influenza
Pneumococcus is known as an opportunistic infection because it lives in the respiratory tract of people without causing disease, but when the respiratory tract is compromised by an infection such as influenza, the bacteria then invades the lungs , bloodstream , or brain and spinal cord . Activities like smoking can also disrupt the lining of the nose and throat and allow for pneumococcal infections and subsequent disease.
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A Look At Each Vaccine: Pneumococcal Vaccine
Much like Haemophilus influenzae type b , pneumococcal bacteria affect the most defenseless of the population . The diseases caused by pneumococcus include meningitis , bloodstream infections and pneumonia . The pneumococcal vaccine was first introduced for use in all infants in the United States in 2000. Before the vaccine, every year pneumococcus caused about 700 cases of meningitis, 17,000 cases of bloodstream infections, 200 deaths and 5 million ear infections in children.
Infants and young children are at greatest risk of serious infection because they are unable to develop immunity to the sugar that coats the bacteria, something that older children can do when they are more than 2 years of age.
How Much Does It Cost
For adults over age 65 who have Medicare Part B, both pneumococcal vaccines are completely covered at no cost, as long as they are given a year apart.
If you have private insurance or Medicaid, you should check with your individual plan to find out if the vaccines are covered. Usually, routinely recommended vaccinations, like the pneumococcal vaccines, are covered by insurance companies without any copays or coinsurance. This means you can often get the vaccines at little or no cost.
If you need to pay out of pocket for the vaccines, you can review prices for PCV13 and PPSV23.
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What You Need To Know About Pneumonia And Flu Shots
This article was first published in The Montreal Gazette.
Recently, Oprah got pneumonia. Then she went on Ellen to recommend that everyone get their flu and pneumonia shots. Given that only 42 per cent of Canadians over the age of 65 got the pneumonia vaccine in 2016, maybe Oprah can get us over the 80 per cent target.
Sadly, Oprah has not always been a strong advocate for science. She gave a platform to Jenny McCarthy when she started claiming that vaccines caused her sons autism, and she also introduced the world to Dr. Oz.
But as Oprah explained to Ellen, pneumonia is no joke. Around 1.5 million people are hospitalized with pneumonia every year. Around 100,000 die in hospital and a third of people hospitalized with pneumonia die within the year.
Older patients are at greater risk and so are those with pre-existing lung disease. Smoking is also a risk factor for pneumonia, so if you need an extra incentive to stop smoking, this is it. But the main way to prevent pneumonia is with vaccines.
The problem with the pneumonia vaccine is not one of efficacy. A Cochrane meta-analysis of 18 randomized trials found that the pneumonia vaccine led to a substantial reduction in infections. The problem is which pneumonia vaccine to give people.
And if you wont listen to me, at least listen to Oprah.
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How Often Do You Need To Get The Pneumonia Vaccines
Sometimes, vaccines require a booster shot. This means that an additional shot is given after the initial one to make sure that you dont lose immunity over time.
PCV13 never requires a booster shot in children or adults after all recommended doses are received.
Sometimes, PPSV23 requires a booster shot, depending on when and why it was given:
Children who get PPSV23 due to certain health conditions, like cancer and conditions that weaken the immune system, need a booster 5 years after the first dose.
Adults who get PPSV23 before age 65 should get one booster at least 5 years after the first dose, once theyve turned 65. No booster is needed if the first dose is given after age 65.
Adults with a weakened immune system and other specific conditions should have another dose 5 years after their first dose, and then one more dose at least 5 years after their most recent dose, once theyve turned 65.
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An Ounce Of Prevention Is Worth A Pound Of Cure
In the 1940s all of the strains of pneumococcus could be treated with the antibiotic, penicillin. However, over time many pneumococcal strains have become resistant not only to penicillin, but also to other antibiotics developed to combat bacterial infections. Resistance means that bacteria have changed, or evolved, so that they are no longer killed by one or more antibiotics. As a result, treatment with those antibiotics is not effective against those resistant strains.
Strains of pneumococcus have now been identified that are highly resistant to most antibiotics. Our reliance on and overuse of antibiotics have led to this resistance, backing us into a corner when treating infections caused by these and other types of bacteria. Unfortunately, we have taken our first steps into a post-antibiotic era. This makes the use of vaccines all the more important.
Side Effects Of The Pneumococcal Vaccine In Adults And Older Children
Mild side effects of the pneumococcal polysaccharide vaccine , the version of the pneumococcal vaccine given to adults and children over the age of 2, include:
- mild soreness or hardness at the site of the injection lasting 1 to 3 days
- a slightly raised temperature
More serious side effects of the PPV vaccine, such as allergic reactions, are rare.
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Children At High Risk Of Ipd
Infants at high risk of IPD due to an underlying medical condition should receive Pneu-C-13 vaccine in a 4 dose schedule at 2 months, 4 months and 6 months followed by a dose at 12 to 15 months of age. Table 3 summarizes the recommended schedules for Pneu-C-13 vaccine for infants and children at high risk of IPD due to an underlying medical condition by pneumococcal conjugate vaccination history.
In addition to Pneu-C-13 vaccine, children at high risk of IPD due to an underlying medical condition should receive 1 dose of Pneu-P-23 vaccine at 24 months of age, at least 8 weeks after Pneu-C-13 vaccine. If an older child or adolescent at high risk of IPD due to an underlying medical condition has not previously received Pneu-P-23 vaccine, 1 dose of Pneu-P-23 vaccine should be administered, at least 8 weeks after Pneu-C-13 vaccine. Children and adolescents at highest risk of IPD should receive 1 booster dose of Pneu-P-23 vaccine refer to Booster doses and re-immunization. Refer to Immunocompromised persons for information about immunization of HSCT recipients.
Table 3: Recommended Schedules for Pneu-C-13 Vaccine for Children 2 months to less than 18 years of age, by Pneumococcal Conjugate Vaccination History
|Age at presentation for immunization||Number of doses of Pneu-C-7, Pneu-C-10 or Pneu-C-13 previously received|
How Long Does A Pneumonia Shot Last
Streptococcus pneumoniaevaccinepneumoniaStreptococcus pneumoniae
- Younger than 2 years old: four shots
- 65 years old or older: two shots, which will last you the rest of your life
- Between 2 and 64 years old: between one and three shots if you have certain immune system disorders or if youre a smoker
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Problems That Could Happen After Getting Any Injected Vaccine
- People sometimes faint after a medical procedure, including vaccination. Sitting or lying down for about 15 minutes can help prevent fainting and injuries caused by a fall. Tell your doctor if you or your child:
- Feel dizzy
- Have vision changes
- Have ringing in the ears