When To Get Vaccinations Against Viral Causes Of Meningitis
Unfortunately, there isnt a vaccine for the most common cause of viral meningitis called non-polio enteroviruses. In rare cases, other kinds of viral infections can lead to meningitis. These viral infections have vaccines that are available in the U.S. They include:
The vaccinations for these infections all have their own schedule for when you should get them the most frequent being your yearly flu shot. Measles and mumps vaccinations are first completed around the age of six then need to be updated in adolescence and adulthood. Talk to your doctor to make sure that youre up-to-date with your vaccinations.
Meningococcal Acwy Vaccine Side Effects
The meningococcal ACWY vaccine is effective and safe, although all medications can have unwanted side effects.
Side effects from this vaccine are uncommon and are usually mild, but may include:
- localised pain, redness and swelling at the injection site
- occasionally, an injection-site lump that may last many weeks
- low-grade temperature
- children being unsettled, irritable, tearful, or generally unhappy, drowsy and tired.
Menb Vaccination Of Adolescents
Adolescents and young adults may also receive a serogroup B meningococcal vaccine. The preferred age for receipt is 16 through 18 years so adolescents have protection during the ages of increased risk.
Patients taking complement inhibitors, such as eculizumab or ravulizumab , are at increased risk for meningococcal disease. These patients may still contract meningococcal disease despite being fully vaccinated or receiving antimicrobial prophylaxis.
CDC recommends that certain adolescents and young adults should receive a serogroup B meningococcal vaccine. They include those at increased risk because of a serogroup B meningococcal disease outbreak and people with certain medical conditions or taking certain medications. These include
- Complement component deficiency
- Functional or anatomic asplenia
- Complement inhibitor
Those at increased risk need regular booster doses.
- Administer a booster dose of MenB vaccine 1 year after series completion and then every 2 to 3 years thereafter.
- For those at increased risk due to an outbreak who previously received the MenB vaccine series, CDC recommends a booster dose if a year or more has passed since primary series completion.
See Meningococcal Vaccination for Adolescents: Information for Healthcare Professionals for additional information.
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Contraindications And Precautions Of Meningococcal Vaccine
The main contraindication for meningococcal vaccines is
For children with functional or anatomic asplenia, MenACWY and pneumococcal conjugate vaccine is caused by some of the > 90 serotypes of Streptococcus pneumoniae . Vaccines are directed against… read more ) should not be given during the same visit but should be separated by 4 weeks.
Ingredients In Menb Vaccines
Meningitis B vaccines, like Bexero and Trumenba, are made up of three proteins found on the surface of one subtype of the Neisseria meningitidis bacteria. The specific proteins differ, depending on whether you receive Bexsero or Trumenba.
These vaccine contains very small amounts of other ingredients, like aluminum hydroxide, sucrose , histidine , and sodium chloride .
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Are Both Meningococcal Vaccines Equally Effective
The MCV4, MPSV4 and MenB vaccines are about 85-90% effective in preventing meningococcal disease. There are actually several types of N meningitidis — the bacterium that causes meningococcal disease, five of which are common in the U.S. These vaccines together protect against all five of these strains.
MCV4 has not been available long enough to compare the long-term effectiveness of the two vaccines. But most experts think that MCV4 provides better, longer-lasting protection.
What Are The Options For Meningococcal Vaccine
Meningococcal vaccine is highly effective at protecting against four strains of the meningococcal bacteria. Three strains are common in the United States and the fourth strain protects travelers to certain countries where the disease is more common.
The MenACWY vaccine does not contain the meningococcal B strain that is more commonly found in infants and may cause some cases in adolescents. There is an additional vaccine, meningococcal B vaccine , that contains the B strain. If your clinic does not carry the MenB vaccine, you can ask them to order it for you, or to refer you to another clinic that has the vaccine. Talk to your health care provider about getting this additional vaccine.
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Common And Local Adverse Events
Conjugate meningococcal vaccines
Men-C-ACYW vaccines
Injection site reactions occur in up to 59% of vaccinees. Fever is reported in up to 5% of recipients and systemic reactions, such as headache and malaise, are reported in up to 60% of recipients.
Men-C-C vaccines
Mild reactions, including injection site reactions , occur in up to 50% of vaccine recipients. Irritability occurs in up to 80% of infants and fever in up to 9% when other vaccines were administered. Headaches and malaise occur in up to 10% of older children and adults. These reactions last no more than a few days.
Serogroup B Meningococcal vaccines
4CMenB vaccine
Solicited local and systemic reactions have been commonly reported in clinical trials and include injection site tenderness, induration, sleepiness and irritability. Higher rates of fever have been observed with simultaneous administration of 4CMenB vaccine and routine infant vaccines therefore, routine prophylactic administration of acetaminophen or separating 4CMenB vaccination from routine vaccination schedule has been proposed for preventing fever in infants and children up to three years of age.
MenB-fHBP vaccine
Solicited local and systemic reactions have been commonly reported in clinical trials and include injection site tenderness, induration and irritability.
Number And Timing Of Doses
Vaccinate all children younger than 2 years old with PCV13. The primary series consists of 3 doses routinely given at 2, 4, and 6 months of age. You can administer the first dose as early as 6 weeks of age. CDC recommends a fourth dose at 12 through 15 months of age. For children vaccinated when they are younger than 12 months of age, the minimum interval between doses is 4 weeks. Separate doses given at 12 months of age and older by at least 8 weeks.
The number and timing of doses for older children and adults depends on the medical indication, prior pneumococcal vaccination, and age. See Pneumococcal Vaccination: Summary of Who and When to Vaccinate for all pneumococcal vaccine recommendations by vaccine and age.
Summarizes how to implement adult pneumococcal vaccination recommendations.
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Are There Times You Shouldn’t Get The Vaccine
Typically, you want to avoid getting it if you:
- Are very sick. A mild cold is OK, but for anything more than that, it’s better to hold off.
- Had a severe, life-threatening allergy to a meningitis vaccine or some part of it. Your doctor can tell you what’s in the vaccine.
- Had a severe reaction to the DTap vaccine or latex
- Have Guillain-Barre syndrome. Ask your doctor if the vaccine is safe for you.
- Have a latex allergy
May be pregnant or are breastfeeding. It’s typically best to avoid the vaccine in this case, but if it’s needed, your doctor can help weigh the pros and cons.
Concerns About Immunisation Side Effects
If a side effect following immunisation is unexpected, persistent or severe, or if you are worried about yourself or your childs condition after an immunisation, see your doctor or immunisation nurse as soon as possible or go directly to a hospital.
It is important to seek medical advice if you are unwell, as this may be due to other illness rather than because of the vaccination.
In Victoria you can report immunisation side effects to SAEFVIC, the vaccine safety and central reporting service on Tel. 1300 882 924 #1. Ask your immunisation provider how to report adverse events in other states or territories.
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Rare Side Effects Of Meningococcal Immunisation
There is a very small risk of a serious allergic reaction to any vaccine. This is why you are advised to stay at the clinic or medical surgery for at least 15 minutes following immunisation in case further treatment is required.
If any other reactions are severe and persistent, or if you are worried, contact your doctor for further information.
Ingredients In Menacwy Vaccines
Menactra, MenQuadfi, and Menveo are all made through a process which chemically links a protein recognized by the immune system with a sugar molecule found on the surface of certain types of Neisseria meningitidis.
Usually, those polysaccharides are hard for the immune system to spot, but when theyre linked to proteins the immune system recognizes, your body learns to mount a response to it. These vaccines are called conjugate vaccines.
Importantly, each one of these vaccines contains polysaccharides from four different serogroups of Neisseria meningitidis.That allows the vaccine to protect you against four different subgroups of bacteria.
These vaccines do not contain preservatives or adjuvants .
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What Are The Side Effects From The Meningococcal Vaccines
With any vaccine, there is the potential of a severe allergic reaction within a few minutes to a few hours after the shot. But the likelihood that the meningococcal vaccines would cause a severe reaction is extremely slight.
About one out of every two people who get the shot experience mild reactions such as redness or a mild pain where the shot was given. Those usually go away in one to two days. A small percentage of people develop a mild fever.
There have been reports that a few people have been diagnosed with Guillain-Barre syndrome after receiving MCV4. But experts say it occurs so rarely that it’s not possible to tell if it’s related to the vaccine or coincidental.
You Are Pregnant Or Breastfeeding
- Pregnant women who are at increased risk for serogroup A, C, W, or Y meningococcal disease may get MenACWY vaccines.
- Pregnant or breastfeeding women who are at increased risk for serogroup B meningococcal disease may get MenB vaccines. However, they should talk with a doctor to decide if the benefits of getting the vaccine outweigh the risks.
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Types Of Meningococcal Vaccines
The first category of vaccine is called the meningococcal conjugate vaccines or MenACWY vaccines. This vaccine protects against four strains of bacteria that fall into serogroups A, C, W, and Y.
Serogroups are closely related groups of bacteria that all present the same calling cards to the immune system. The MenACWY vaccine protects against meningitis-causing bacteria that present with the A, C, W, or Y calling cards.
Three types of MenACWY vaccines are currently available:
- Menactra
- Menveo
- MenQuadfi
The second category of meningococcal vaccines protects against bacteria that fall into serogroup B. These are called MenB vaccines and are sold under the brand names Bexsero and Trumenba.
The MenB vaccine is fairly new. The FDA approved Trumenba in 2014. Bexsero was approved in 2015. MenB vaccine is not currently part of the U.S. standard childhood vaccine immunization schedule. But in other countries, like the United Kingdom, Bexsero is routinely given during infancy.
When To Get Vaccinations Against Bacterial Causes Of Meningitis
Meningitis is a disease thats defined by inflammation in membranes called meninges near your brain and spinal cord. It can have several different causes including viruses, bacteria, fungi, and some chemicals.
Different vaccines can protect you from the different causes of meningitis. Each has its own schedule for when you should receive it. Youll first get some of these vaccinations as an infant and others as a teenager or even as an adult. Many require boosters at various points throughout your life particularly if youre in a high-risk category for getting meningitis.
In general, vaccines are most helpful for protecting against bacterial meningitis, which is less common but more severe than viral meningitis.
Meningococcal vaccines protect against the meningitis-causing bacteria N. meningitidis. Two vaccines are currently approved for use in the U.S. Theyre called the MenACWY vaccine and the MenB vaccine.
The MenACWY vaccine is recommended for all young adults around the age of 11 or 12 years old plus a booster shot at 16 years. Another meningococcal vaccine called MenB is recommended between the ages of 16 to 18.
A good question to ask is: how long does the meningitis vaccine last? Even though both meningococcal vaccines produce an immune response, they lose effectiveness over time.
Healthy adults wont require another dose of this vaccine. But you should talk to your doctor about getting another pneumococcal vaccine if youre 65 years or older.
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Can Menb Disease Be Prevented
Yes. This vaccine helps protect babies against MenB and there are other vaccines, like MenC, that protect against some other types of meningococcal infections.
Immunising babies helps protect them when they’re most at risk of developing meningococcal disease.
Meningitis and septicaemia are very serious diseases that need urgent medical treatment. Some of the symptoms are very similar to the symptoms of flu, so, if youre in any doubt about your babys health, trust your instincts and get advice urgently by phoning your GP, or the 111 service if your GP is closed.
Routine Menacwy Vaccination Of Adolescents
All 11 to 12 year olds should receive a meningococcal conjugate vaccine. Since protection wanes, CDC recommends a booster dose at age 16 years. The booster dose provides protection during the ages when adolescents are at highest risk of meningococcal disease.
- For adolescents who receive the first dose at age 13 through 15 years, administer a booster dose at age 16 through 18 years, before the period of increased risk.
- Adolescents who receive their first dose of MenACWY vaccine at or after age 16 years do not need a booster dose.
- Adolescents who are at increased risk due to medical conditions need a 2-dose primary series of MenACWY vaccine administered 8 weeks apart, as well as regular booster doses every 5 years.
- CDC also recommends a booster dose for those at increased risk due to an outbreak if 5 or more years have passed since receiving MenACWY.
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Is It Possible To Get The Vaccine And Still Get Meningitis
Because the vaccines do not protect against all causes of meningitis, it is still possible that someone could receive the vaccine and still get meningitis from a different strain not protected by the vaccine. But the risk of contracting meningococcal meningitis is significantly lower after the vaccine.
There are other causes of meningitis that are preventable. Vaccines like the Hib vaccine and the pneumococcal vaccine are also very effective at protecting against other causes of meningitis and should be included as part of a routine childhood vaccination schedule. Check with your doctor and your children’s doctor to make sure that you and your family are protected against meningitis, as well as other serious illnesses.
When Do I Need To Get The Meningitis Vaccine And How Often
âIt is routine for children who go to the pediatrician at age 11 or 12 to receive this vaccine. When children get older and leave home, almost every college requires or strongly recommends that students be vaccinated before they come to campus.â
âAt the moment, this is a one-dose immunization, but the CDC is now discussing whether children who receive the vaccine at 11 or 12 years old need a booster shot just before college. I recommend students and parents stay tuned for more info, which could be coming as soon as mid-2011.â
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Are There Any Adults Who Should Not Get The Meningococcal Vaccine
You shouldn’t get either type of meningococcal vaccine if you:
- Are moderately or seriously ill wait until you recover.
- Have had a serious allergic reaction to a previous dose
- Had a severe reaction to any part of the vaccine
If you are pregnant or have other concerns, ask your doctor which meningitis vaccine is right for you.
Who Needs A Meningococcal Vaccine
The CDC recommends a meningococcal vaccine for:
- All children ages 11-18 or certain younger high-risk children
- Anyone who has been exposed to meningitis during an outbreak
- Anyone traveling to or living where meningitis is common, such as in sub-Saharan Africa
- Military recruits
- People with certain immune system disorders or a damaged or missing spleen
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Is The Meningitis B Vaccine Safe
In the same 2021 study mentioned above, researchers found the vaccine demonstrated an acceptable level of safety. No safety concerns have been raised based on current data, which includes more than 3 million doses administered in the United Kingdom.
Data from Quebec revealed four cases of a kidney disorder called nephrotic syndrome in children age 2 to 5 within 13 months of receiving their vaccine. Researchers are still trying to understand if theres a link, but a lack of similar findings from other countries suggests these cases may have occurred by chance.
Side effects of meningitis B are usually mild and last for
What Happens After The Immunization
Your child might have a fever, soreness, and some swelling and redness at the injection area. Check with your doctor to see if you can give either acetaminophen or ibuprofen for pain or fever and to find out the right dose.
A warm, damp cloth or a heating pad on the injection site may help reduce soreness, as can moving or using the arm.
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Why Do Teens Need A Meningococcal Vaccine
Of the 1,000-2,600 people who get meningococcal disease each year, one-third are teens and young adults. Ten percent to 15% of those who get sick with the disease will die, even with antibiotic treatment. As many as 20% of the survivorswill have permanent side effects, such as hearing loss or brain damage.
The immunization can help prevent this serious disease.