Uncommon Rare And Very Rare Adverse Events
Uncommon adverse events occur in 0.1% to less than 1% of vaccinees. Rare and very rare adverse events occur, respectively, in 0.01% to less than 0.1% and less than 0.01% of vaccinees.
Both HZ vaccines are safe with serious adverse events reported very rarely in immunocompetent individuals.
Recurrence or exacerbation of herpes zoster ophthalmicus following LZV vaccination has been reported very rarely, involving several cases world-wide following LZV immunization. Following a causality assessment of seven cases of HZO which were temporally associated with the administration of LZV, NACI concluded that there was insufficient evidence to recommend for or against the administration of LZV in individuals with a history of HZO. More evidence is required for further assessment of risk related to HZO recurrence in LZV recipients. At this time, there is insufficient evidence to assess the risk related to HZO recurrence following RZV recipients.
See Contraindications and Precautions if considering vaccinating a person with previous HZO.
For more information, refer to Vaccine safety in Part 2 and the product monograph in Health Canada’s Drug Product Database.
What Are The Shingles Vaccines
There are 2 vaccines, Shingrix® and Zostavax® II, that protect against shingles. Shingles is caused by the varicella zoster virus, which also causes chickenpox. Zostavax® II contains a weakened form of the virus while Shingrix® contains only a part of the virus. The vaccines are approved by Health Canada.
How Effective Is The Shingles Vaccine
Having the shingles vaccine reduces your risk of getting shingles and post-herpetic neuralgia, but the effect of the vaccine differs by age and time since vaccination. Age at which you get vaccinatedThe shingles vaccine is most effective at preventing shingles in people aged 5059 years and becomes less effective as you get older. It is effective in about 5 in 10 people aged 6569 years and about 4 in 10 people aged 80 years or older. Times since vaccinationProtection from the shingles vaccine wears off over time. The highest protection against shingles is during the first year after receiving the vaccine. By 6 years after being vaccinated, protection is very low. Booster dosesThere is no information about whether a booster dose of the shingles vaccine provides any benefit. Although there are no recommendations, adults who have previously received the shingles vaccine can receive a second dose after 1 year. There are no safety concerns about receiving a second dose.
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What Are The Symptoms Of Shingles
Shingles is a painful rash that develops on one side of the face or body. The rash forms blisters that typically scab over in 7-10 days. Shingles typically takes 2-4 weeks to clear up.
People often feel pain, itching, or tingling in the area 1-5 days before the rash appears.
Most commonly, shingles forms a single stripe of rash on either the left or right hemisphere of the body. Occasionally, the rash occurs on one side of the face. Less commonly, the rash looks similar to chickenpox and is spread more liberally . Shingles can sometimes affect the eyes and cause loss of vision.
Other symptoms of shingles can include fever, headache, chills and upset stomach.
What Happens When You Get The Vaccine

As mentioned above, there are two options for the shingles vaccine: Zostavax and Shingrix.
Zostavax has been used in the U.S. since 2006. Its a single-dose injection given subcutaneously, right beneath the skins surface in the upper arm. About 40% of people experience some pain as a result of the shot and it is a live vaccine, which typically isnt recommended for anyone with a compromised immune system.19
Studies show Zostavax reduced the risk of developing shingles by nearly 70% in those ages 50 to 59, and by over 50% at age 60 and above. Its effectiveness drops to only 18% for people who are over 80,20 and its protection wanes after about five years.21
Although Shingrix is the newer vaccine , Zostavax is still recommended by the CDC for healthy adults aged 60 and over.22
Shingrix, which contains no live virus, is a two-dose vaccine series given in the muscle of the upper arm. The second shot is given two to six months after the first. In clinical trials, it was effective in nearly 97% of adults in their 50s over 97% effective for people in their 60s and over 91% effective for those aged 70 and above. It remains at near 85% effectiveness in all four years following vaccination.23 Because it is more effective, the CDC now recommends Shingrix over Zostavax.
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Who Needs The Shingles Vaccine
According to the Centers for Disease Control and Prevention , the Advisory Committee on Immunization Practices recommends the shingles vaccine for people 50 and older. It is a manufactured inactivated vaccine intended to prevent shingles. The vaccine is administered in two separate doses given by intramuscular injection, separated by two to six months.
The shingles vaccine is considered an important vaccine for seniors because our immune system weakens as we age. The recommendation for vaccination is based on the potential severity of symptoms and long-term complications.
A shingles vaccine called Zostavax is no longer used in the United States as of November 2020. If you received that vaccine, the CDC recommends talking with your doctor about getting the Shingrix vaccine.
The CDCs fact sheet on shingles lists these risks and potential complications: |
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Shingrix is more than 90% effective at preventing shingles, but it does not prevent chickenpox.
Who Should Not Get Vaccinated Or Should Wait
- Patients with a history of severe allergic reaction to any component of the vaccine or after a previous dose of Shingrix
- Patients who tested negative for immunity to varicella zoster virus. If you test negative, you should get the chickenpox vaccine.
- Patients who currently have shingles
- Patients who are currently pregnant or breastfeeding. Women who are pregnant or breastfeeding should wait to get Shingrix.
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What Are The Possible Side Effects Of Shingrix
Studies show that Shingrix is safe. The vaccine helps your body create a strong defense against shingles. As a result, you are likely to have temporary side effects from getting the shots. The side effects may affect your ability to do normal daily activities for 2 to 3 days.
Most people got a sore arm with mild or moderate pain after getting Shingrix, and some also had redness and swelling where they got the shot. Some people felt tired, had muscle pain, a headache, shivering, fever, stomach pain, or nausea. About 1 out of 6 people who got Shingrix experienced side effects that prevented them from doing regular activities. Symptoms went away on their own in about 2 to 3 days. Side effects were more common in younger people.
You might have a reaction to the first or second dose of Shingrix, or both doses. If you experience side effects, you may choose to take over-the-counter pain medicine such as ibuprofen or acetaminophen.
If you experience side effects from Shingrix, you should report them to the Vaccine Adverse Event Reporting System . Your doctor might file this report, or you can do it yourself through the VAERS websiteexternal icon, or by calling 1-800-822-7967.
If you have any questions about side effects from Shingrix, talk with your doctor.
The shingles vaccine does not contain thimerosal .
Why Doesn’t Medicare Cover The Shingles Vaccine As Free For All Seniors
Many people think that a vaccine that’s recommended by the CDC for those over age 50 would be fully covered by Original Medicare. However, there are a few reasons why you may end up paying hundreds of dollars for the two-dose regimen.
- Medicare coverage levels: Some Medicare drug plans have better cost-sharing benefits than others, and how much you pay for the shingles vaccine will depend on the plan you choose.
- Pharmaceutical classification: Medicare classifies the Shingrix vaccine as a part of its pharmaceutical coverage, meaning it would fall under Medicare Part D coverage rather than Part A or Part B. In contrast, most private health insurance, either through an employer or through the marketplace, classifies the shingles vaccine as a part of its free preventative coverage.
- Type of pharmaceutical: Shingrix is a Tier 3 drug made by GlaxoSmithKline, and there isn’t a generic alternative. This could mean that your out-of-pocket costs are higher than other medications.
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Herpes Zoster Vaccine: Canadian Immunization Guide
For health professionals
Last complete revision:
July 2018 This chapter was revised to reflect NACI’s Updated Recommendations on the Use of Herpes Zoster Vaccines. Most sections were revised to include information and practice recommendations for the new recombinant zoster vaccine which is now available in Canada. Changes include:
- Recommendations for use in different populations.
- Contraindications and precautions.
- Administration of the HZ vaccines: Table 1 was added to summarize key information.
- Considerations on the efficacy, effectiveness and immunogenicity of HZ vaccines: Table 2 was added to summarize key information.
- Vaccine safety and adverse events.
Is Shingrix Covered By Medicare
Yes, all Medicare Part D plans cover this drug, and Medicare Advantage plans with built-in Part D coverage will also cover Shingrix. Also, you may not need a prescription if you are paying for this drug yourself.
Simply so, will Medicare pay for Shingrix in 2019?
Please note, the new shingles vaccine Shingrix® , is now available on most Medicare Part D plans and Medicare Advantage plans that include drug coverage. Shingrix is the preferred vaccine, over Zostavax®, a shingles vaccine in use since 2006.”
Additionally, how much is the shingles vaccine at Walgreens? Cost may be part of the reason so few get the shot. The Shingrix vaccine costs $280. Zostavax costs around $200.
Likewise, people ask, how much does Shingrix cost?
Shingrix costs $280 for both shots.
How much does the new shingles vaccine cost?
Availability and CostAccording to Schaffner, it’s anticipated that deductibles and co-pays aside, private insurers will probably cover the cost of Shingrixwhich is $280 for the two shots. That’s what insurers generally do with Zostavax .
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What Kinds Of Vaccines Does Cvs Offer
CVS Pharmacy offers a full list of vaccines. Among the most commonly requested ones are:
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Influenza : The flu vaccine is offered on a seasonal basis. Two different kinds are available. Four-strain flu vaccine protects against four strains of the virus for children and adults. The high-dose or senior-dose flu vaccine is for people age 65 and older.
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Shingles: The shingles vaccine is recommended for people age 50 and older. It is given in two doses spaced 2 to 6 months apart.
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COVID-19: The long-awaited coronavirus vaccine is finally available to all adults age 16 and older starting April 19 and earlier in many places. A vaccine for younger teens and children is expected later this year.
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Tdap: The CDC recommends the combination tetanus, diphtheria, and pertussis vaccine for adolescents and adults every 10 years to protect against all three infections.
Each state has its own age requirements and other vaccine restrictions, so be sure to check your local stores rules before heading to CVS.
Know Your Risk Of Getting Shingles And Complications

About 1 out of every 3 people in the United States will develop shingles during their lifetime.
If youve had chickenpox, you are at risk for shingles. More than 99% of Americans born before 1980 have had chickenpox, even if they dont remember it.
Your risk of getting shingles and having serious complications increases as you get older.
About 1 in 10 people who get shingles develop nerve pain that lasts for months or years after the rash goes away. This is called postherpetic neuralgia and is the most common complication of shingles.
Shingles may lead to other serious complications involving the eye, including blindness. Very rarely, it can also lead to pneumonia, hearing problems, brain inflammation or death.
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You Can Get A Shingles Vaccine Two Ways:
At the pharmacy. Youll still need a doctors prescription, but once thats been transmitted, you can get the shot at a retail pharmacy.
Most major chains and some independent pharmacies can administer the vaccine. Just make sure to use a store in your drug plans network so that it can bill your plan directly and youll owe just the copayment.
At the doctors office. If youre vaccinated in a doctors office, check whether it can bill your drug plan directly or works with a pharmacy that can do so. If so, it will work as mentioned above, with you owing a copayment. If not, you may need to pay the full cost up front and then file a claim for reimbursement from your plan.
Remember that the doctors fee for administering the vaccine may exceed your plans allowable charge, in which you case youre on the hook for the difference. It pays to check beforehand.
Editor’s note: This article was originally published on Jan. 1, 2014. It has been updated with the latest information regarding Medicare coverage in 2020.
About The Shingles Vaccine
The Centers for Disease Control and Prevention recommends that healthy adults over the age of 50 get the shingles vaccine because it’s the only way to protect against the disease and its associated side effects. The risk of getting shingles increases as you age or if you have a weakened immune system. Always consult your doctor to find out if the shingles vaccine is right for you.
The CDC recommended vaccine, Shingrix, is a recombinant zoster vaccine that has two doses administered within six months of each other. It’s classified as a Tier 3 drug by most insurance companies, which means it’s a brand-name pharmaceutical with a higher copayment than a Tier 1 or 2 drug.
Use the Shingrix vaccine locator to find where the shingles vaccine is being offered, and check with your Medicare Part D or Medicare Advantage provider to see which locations give you the lowest price.
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How Well Does Shingrix Work
Two doses of Shingrix provides strong protection against shingles and postherpetic neuralgia , the most common complication of shingles.
- In adults 50 to 69 years old who got two doses, Shingrix was 97% effective in preventing shingles among adults 70 years and older, Shingrix was 91% effective.
- In adults 50 to 69 years old who got two doses, Shingrix was 91% effective in preventing PHN among adults 70 years and older, Shingrix was 89% effective.
Shingrix protection remained high in people 70 years and older throughout the four years following vaccination. Since your risk of shingles and PHN increases as you get older, it is important to have strong protection against shingles in your older years.
What Everyone Should Know About The Shingles Vaccine
Shingles vaccination is the only way to protect against shingles and postherpetic neuralgia , the most common complication from shingles. CDC recommends that healthy adults 50 years and older get two doses of the shingles vaccine called Shingrix , separated by 2 to 6 months, to prevent shingles and the complications from the disease. Your doctor or pharmacist can give you Shingrix as a shot in your upper arm.
Shingrix provides strong protection against shingles and PHN. Two doses of Shingrix is more than 90% effective at preventing shingles and PHN. Protection stays above 85% for at least the first four years after you get vaccinated.
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How Well Does The Shingles Vaccine Work
The effect of the shingles vaccine depends on the age at which you get vaccinated.The shingles vaccine is most effective at preventing shingles in people aged 5059 years and becomes less effective as you get older. About 5 in 10 people aged 6569 years and 4 in 10 people aged 80 years or older are protected.Although vaccination may not prevent herpes zoster in some older adults, studies suggest that vaccination boosts enough immunity to reduce herpes zoster pain and the risk of post-herpetic neuralgia.
Concerned About Shingles Free Vaccine Available
The shingles vaccine is available to adults age 50 years and older. This vaccine is covered by Ontario Health Insurance Plan only for those aged 65-70 years old. For other age groups, there is a cost which may be covered by your insurance benefit plan.
Shingles or herpes zoster is caused by the virus that causes chickenpox. Once a person has had chickenpox, the virus stays in the nerve cells of the body. The virus may be there for many years and not cause any problems. Sometimes, for unknown reasons, it becomes active again and causes shingles. Shingles causes a painful, blistering skin rash.
Not everyone who has had chickenpox will develop shingles it occurs most frequently in adults over age 50 and in people with a weakened immune system. Zostavax is available from your health care provider or you can book into one of our immunization clinics held twice a month. Only 1 dose is needed for protection.
Note: A newly released zoster vaccine, Shingrix is currently not available at the CK Public Health.
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