Thursday, September 21, 2023

When Is Meningitis Vaccine Given

Is It Too Late To Get Vaccinated

‘Meningitis vaccine should be given to children of all ages’ – Daily Mail

The answer to this question isnt so clear-cut. If you have an unvaccinated teen headed off to college, there is still time for them to get their vaccines. Your child may also need another shot if they had the vaccine as a preteen. Meningitis vaccines are thought to only last for about five years, according to the Center for Young Womens Health.

Adults can also get the meningitis vaccine if their doctors recommend it. Certain situations can warrant the use of meningitis vaccinations. Examples include spleen removal, going to military camp, or traveling overseas.

How Do We Know The Vaccine’s Safe

All medicines are tested for safety and effectiveness by the Medicines and Healthcare Products Regulatory Agency . The vaccine meets the high safety standards required for it to be used in the UK and other European countries. The vaccine has been given to millions of people worldwide.

Once they’re in use, the safety of vaccines continues to be monitored by the MHRA.

How Do Meningococcal Bacteria Spread

Meningococcal disease is caused by 13 different groups of meningococcal bacteria.

In the UK, the disease is almost always caused by 1 of 4 meningococcal groups commonly known as MenB, MenC, MenW or MenY. These can be prevented with vaccination.

MenA disease is rare in the UK, but it’s more common in other parts of the world. It can also be prevented by vaccination.

The meningococcal bacteria live in the back of the nose and throat in about 1 in 10 people without causing any symptoms or illness.

Older teenagers are most likely to carry and spread the meningococcal bacteria.

The bacteria are spread from person to person by prolonged close contact such as coughing, kissing or sneezing with someone who is carrying the bacteria.

Very occasionally, the meningococcal bacteria can cause serious illness, including meningitis and septicaemia, which can rapidly lead to sepsis.

Meningococcal infections can happen at any age, but babies, young children and teenagers are especially vulnerable.

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When To Get Vaccinated

The key to the meningitis vaccines is to make sure that your teen gets them at the right time. Your child may get the MCV4 vaccine if they are:

  • Between 11 and 15 years old. After the initial MCV4 vaccine, your teen will get a booster shot after five years.
  • After the age of 16. In this case, your teen wont need the booster shot. Important to note: Its better to get the vaccines earlier rather than later. This will help prevent meningitis during your teens high school years.
  • First-year college students. This applies to those who havent received a diagnosis or missed their booster shots.
  • Those deemed by a pediatrician to need extra protection. This is due to underlying illnesses. Examples include immune system disorders or a damaged spleen.

Technically, the MenB vaccine is approved for children over the age of 10. Your doctor might recommend a dose at a younger age if your child has immune system deficiencies. But MenB is usually taken around the age of 16. The American Academy of Pediatrics recommends MenB shots for teens ages 16 to 18. However, it may be given to young adults up to 23 years old.

Who Should Get Meningococcal Vaccines

New study confirms success of MenB vaccine in the UK

CDC recommends meningococcal vaccination for all preteens and teens. In certain situations, CDC also recommends other children and adults get meningococcal vaccines. Below is more information about which meningococcal vaccines, including booster shots, CDC recommends for people by age.

Talk to your or your childs doctor about what is best for your specific situation.

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Who Should Not Be Immunised

  • There are very few people who cannot be given meningococcal vaccines.
  • Immunisation should be postponed if a child has a high temperature or serious infection. Minor infections such as coughs, colds and snuffles are no reason to postpone immunisation.
  • The vaccine should not be given if there has been a severe reaction to a previous dose of vaccine . Also, it should not be given if a person is known to have a severe allergy to any of the ingredients in the vaccine.
  • The vaccines are safe if you are breastfeeding.

Where And When Can I Get The Vaccine

Talk to your doctor or local public health clinic to find out where and when your child should get vaccinated.

  • The cost of Men-C-C is covered everywhere in Canada.
  • Many provinces currently cover the cost of MCV-4 vaccine.
  • Currently, no provinces or territories cover the cost of Men-B vaccine for all children. Some provide it for children at high risk of getting meningococcal disease.

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Why Do Teens Need A Meningococcal Vaccine

Of the 1,000-2,600 people who get meningococcal disease each year, one-third are teens and young adults. Ten percent to 15% of those who get sick with the disease will die, even with antibiotic treatment. As many as 20% of the survivorswill have permanent side effects, such as hearing loss or brain damage.

The immunization can help prevent this serious disease.

Managing Fever After Meningococcal Acwy Immunisation

SDSU students may need to get another meningitis vaccine

Common side effects following immunisation are usually mild and temporary . Specific treatment is not usually required.

If fever is present, drinking extra fluids and not overdressing can help.

Although routine use of paracetamol after vaccination is not recommended , if fever is present, paracetamol can be given. Check the label for the correct dose according to your childs weight or speak with your pharmacist, especially when giving paracetamol to children.

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What Is Meningitis Or Meningococcal Disease

Meningococcal disease, often called meningitis, is a relatively rare but serious disease caused by the swelling of the protective membranes covering the brain and spinal cord. These illnesses are often severe and include infections of the lining of the brain and spinal cord and bloodstream infections . In 2013, there were 550 cases of meningococcal disease reported in the United States. Meningococcal disease is seasonal, most often occurring in January and February. Teens and young adults ages 16-23 have the highest incidence of disease, which is why the CDC recommends that all children ages 11-18 receive a meningitis vaccine.

How Does Meningitis Spread

Each form of meningitis spreads differently. Viral and bacterial will spread person-to-person through air droplets, kissing or nasal secretions. Fungal and parasitic are ususally cause by environmental factors.

Viral and bacterial are the most common variants. They are most often spread within communities that live or work together. Dorm living, close contact and shared facilities are some common risk areas.

Some regions of the world are at an increased risk for meningitis. These include the meningitis belt in Africa and Saudi Arabia during the Hajj.

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More Information About The Vaccine

The MenB vaccine was introduced into the UK schedule on 1st September 2015. The UK is the first country in the world to introduce a MenB vaccine into its routine vaccination schedule. It is expected that results from the UK programme will influence other countries’ decisions about including the MenB vaccine as part of routine vaccination.

There is a useful list of FAQs about the MenB vaccine on the Meningitis Research Foundation website .

Before 1999, most cases of meningococcal disease in the UK were caused by MenC infection. A MenC vaccination programme was successfully introduced in the UK in 1999. Since then, cases of MenC disease have fallen dramatically in the UK. In the last 10 years, about 90% of the cases of meningococcal disease in the UK have been caused by group B infections. Before the MenB vaccine was introduced around 600 people a year in the UK were infected by MenB, mainly babies and children. About 10% of those who get the disease will die .

Charlotte Nott developed septicaemia through type B meningococcal disease infection. In the short film below, her mother, Jenny Daniels, talks about the impact on Charlotte and the rest of her family.

See also our blog posts on the MenB vaccine in the UK:

Menb Vaccination Of Adults At Increased Risk

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MenB vaccines are not approved for use in people under 10 years old. Adults should receive a MenB vaccine if they are at increased risk for serogroup B meningococcal disease due to

  • Having certain medical conditions
  • Complement component deficiency
  • Functional or anatomic asplenia
  • Taking specific medications
  • Complement inhibitor
  • Working in specific professions or settings
  • Microbiologist who is routinely exposed to Neisseria meningitidis
  • Being a part of a community experiencing a serogroup B meningococcal disease outbreak
  • Those who remain at increased risk need regular booster doses.

    • Administer a booster dose of MenB vaccine 1 year after series completion and then every 2 to 3 years thereafter.
    • For those at increased risk due to an outbreak who previously received the MenB vaccine series, CDC recommends a booster dose if a year or more has passed since primary series completion.

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    Uses For Meningococcal Vaccine

    Meningococcal vaccine is an active immunizing agent used to prevent infection caused by certain groups of meningococcal bacteria . The vaccine works by causing your body to produce its own protection against the disease.

    Menomune® is active against groups A, C, Y and W-135 meningococcal bacteria only.

    Bexsero® and Trumenba® is active against group B meningococcal bacteria only. .

    Meningococcal infection can cause life-threatening illnesses, such as meningococcal meningitis, which affects the brain, and meningococcemia, which affects the blood. Some persons with meningococcal meningitis and/or meningococcemia also may die. These diseases are more likely to occur in young children and in persons with certain diseases or conditions that make them more susceptible to a meningococcal infection or more likely to develop serious problems from a meningococcal infection.

    Immunization against meningococcal disease is recommended for persons who are at risk of getting the disease because:

    • They have certain diseases or conditions that make them more susceptible to a meningococcal infection or more likely to develop serious problems from a meningococcal infection.
    • They are living in, working in, or visiting an area where there is a strong possibility of contracting meningococcal disease.

    Menomune® is recommended for use in patients 2 years of age and older.

    Bexsero® and Trumenba® is recommended for use in patients 10 to 25 years of age. .

    Haemophilus Influenzae Type B Vaccine

    Before a vaccine became available for it, Haemophilus influenzae type b was the leading cause of bacterial meningitis. Hib is much less common today due to vaccinations.

    Doctors usually administer the Hib vaccine at 2, 4, and 6 months of age. They will administer it again between the ages of 12 and 15 months.

    The dosing regimen depends on the brand of vaccine an infant receives.

    Doctors will give this vaccine either alone or as part of a combination vaccine.

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    People Without A Spleen Or Whose Spleen Does Not Work Properly

    If you do not have a spleen, or your spleen does not work properly, or you have a weakened immune system then it is likely to be recommended to you that you receive the MenB and the MenACWY vaccines. The timing of your vaccines will depend on your age. Your doctor will be able to advise you in more detail regarding this.

    Menb Vaccination Of Adolescents

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    Adolescents and young adults may also receive a serogroup B meningococcal vaccine. The preferred age for receipt is 16 through 18 years so adolescents have protection during the ages of increased risk.

    Patients taking complement inhibitors, such as eculizumab or ravulizumab , are at increased risk for meningococcal disease. These patients may still contract meningococcal disease despite being fully vaccinated or receiving antimicrobial prophylaxis.

    CDC recommends that certain adolescents and young adults should receive a serogroup B meningococcal vaccine. They include those at increased risk because of a serogroup B meningococcal disease outbreak and people with certain medical conditions or taking certain medications. These include

    • Complement component deficiency
    • Functional or anatomic asplenia
    • Complement inhibitor

    Those at increased risk need regular booster doses.

    • Administer a booster dose of MenB vaccine 1 year after series completion and then every 2 to 3 years thereafter.
    • For those at increased risk due to an outbreak who previously received the MenB vaccine series, CDC recommends a booster dose if a year or more has passed since primary series completion.

    See Meningococcal Vaccination for Adolescents: Information for Healthcare Professionals for additional information.

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    How To Get The Menb Vaccine

    Your GP surgery or clinic will send you an appointment for your baby to have their MenB vaccination along with their other routine vaccinations.

    Most surgeries and health centres run special immunisation or baby clinics.

    If you cannot get to the clinic, contact the surgery to make another appointment.

    Older Children And The Menacwy Vaccine

    From September 2015 MenACWY began being routinely offered to schoolchildren aged 14-15. . It is also offered to those aged 17-18 and young adults under the age of 25. This is because of a rise in infection with group W meningococcus in this age group.

    If you are under the age of 25 and have not been immunised, see your doctor or practice nurse to get immunised. This is particularly important if you are about to start university for the first time, as the risk of infection with group W meningococcus is highest in first-year university students. Just one injection of vaccine is needed if you are over the age of 1 year.

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    Simultaneous Administration With Other Vaccines

    Men-C-C and 4CMenB vaccine may be administered concomitantly with routine childhood vaccines, and Men-C-ACYW vaccine may be administered concomitantly with adolescent and adult age appropriate vaccines. MenB-fHBP can be given concomitantly with quadrivalent human papillomavirus vaccine meningococcal serogroup A, C, Y, W conjugate vaccine and tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbed. The concomitant administration of MenB-fHBP has not been studied with other vaccines.

    Men-C-ACYW-CRM can be administered with routine paediatric vaccines however, further studies are needed with regard to concomitant administration with pneumococcal 13-valent conjugate vaccine. Co-administration of Men-C-ACYW-CRM and combined tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine may result in a lower immune response to the pertussis antigens than when Tdap vaccine is given alone however, the clinical significance of this is unknown. Tdap vaccine given one month after Men-C-ACYW-CRM induces the strongest immunologic response to pertussis antigens.

    If vaccines are to be administered concomitantly with another vaccine, a separate injection site and a different syringe must be used for each injection.

    Refer to Timing of Vaccine Administration in Part 1 for additional general information.

    People With Medical Conditions That Increase Their Risk Of Invasive Meningococcal Disease

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    People with medical conditions specified in List. Specified medical conditions associated with increased risk of invasive meningococcal disease are strongly recommended to receive MenACWY and MenB vaccines.

    This includes:

    • a full primary course of MenACWY vaccine, with ongoing booster doses
    • a full primary course of MenB vaccine

    People with these specific medical conditions have a higher risk of invasive meningococcal disease. They are recommended to receive extra doses compared with people who do not have these conditions.

    The number of doses needed depends on the vaccine brand used and the persons age when they start the vaccine course.

    For people aged 2 years receiving MenACWY vaccine, it is preferable to receive either Menveo or Nimenrix, rather than Menactra. If Menveo and Nimenrix are unavailable, Menactra can be given.

    There is no preference for either Bexsero or Trumenba for people aged 10 years. For people aged < 10 years, Bexsero is the only registered MenB vaccine available in Australia.

    Bexsero and Trumenba are not interchangeable. The same vaccine should be used for both vaccine doses.

    Regular booster doses are required for MenACWY vaccines, but not for MenB vaccines.

    For more details see:

    People who have previously received a meningococcal polysaccharide vaccine

    They should receive the 1st dose of MenACWY conjugate vaccine about 2 years after the most recent dose of 4vMenPV, with a recommended minimum interval of 6 months.1-3

    Booster doses

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    Persons With Chronic Diseases

    Asplenia

    Two doses of Men-C-ACYW vaccine are recommended for persons with anatomic or functional asplenia, including sickle cell disease. When elective splenectomy is planned, all recommended vaccines should ideally be completed at least 2 weeks before surgery if only one dose can be given before surgery, the second dose should be given 8 weeks after the first dose, with a minimum interval of 4 weeks. In the case of an emergency splenectomy, two doses of vaccine should ideally be given beginning 2 weeks after surgery but can be given earlier, before discharge, if the person might not return for vaccination after discharge. Persons one year of age and older with asplenia who have not received Men-C-ACYW vaccine should receive two doses administered 8 weeks apart, with a minimum interval of 4 weeks. In addition, 4CMenB or MenB-fHBP vaccine should be offered. Periodic booster doses with Men-C-ACYW vaccine are also recommended.

    Refer to Table 1 for vaccination recommendations of high risk individuals due to underlying conditions. Refer to Booster doses and re-immunization for additional information and Immunization of Persons with Chronic Diseases in Part 3 for additional general information.

    What Is Meningococcal Disease

    Meningococcal disease is a serious illness caused by a bacterium. It can cause meningitis, which is an infection of the brain and spinal cord, and it can also cause blood infections. The infection can cause death or lifelong disability.

    About 375 people get the disease each year, and about 10 to 15 out of 100 people infected with meningococcal disease die. Of those who survive, up to one out of five will have permanent disabilities, such as deafness, brain damage, loss of limbs, or seizures.

    A person with meningococcal disease may become seriously ill very quickly. Antibiotics can treat meningococcal infections, but often cant be given soon enough to help.

    Anyone can get meningococcal disease, but it is most common in infants less than 1 year of age. Teens are less likely to be infected than infants, but disease levels increase in adolescence starting around age 11, and peak around age 19 years.

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