Monday, September 25, 2023

When Was The Hpv Vaccine Approved

A Closer Look At The Safety Data

HPV vaccine approved for ages 27 to 45

Findings from many vaccine safety monitoring systems and more than 160 studies have shown that HPV vaccines have a favorable safety profilethe body of scientific evidence overwhelmingly supports their safety.

  • In November 2019, initial post-licensure safety monitoring of Gardasil 9 was published in Pediatrics. In two separate articles, analyses from the Vaccine Adverse Event Reporting System and the Vaccine Safety Datalink were presented. Both included multiple years of data, and did not identify any unexpected safety problems with Gardasil 9. These findings support the favorable safety profile that was established in pre-licensure clinical trials.
  • Analysis from VAERS: Researchers reviewed 7,244 reports submitted to the Vaccine Adverse Event Reporting System following HPV vaccination from December 2014 through December 2017. Of those reports, around 97% were classified as non-serious around 3% were considered serious. The analysis did not detect any new or unexpected safety concerns.Safety of the 9-Valent Human Papillomavirus Vaccine. external icon
  • Analysis from VSD: The Vaccine Safety Datalink conducted near-real time surveillance from October 2015 through October 2017, looking at 11 pre-specified adverse events. During this two-year time period, nearly 840,000 doses were administered to people aged 9-26 years at six VSD sites. No new safety concerns were identified.Near Real-Time Surveillance to Assess the Safety of the 9-Valen Human Papillomavirus Vaccine. external icon

How Much Does Hpv Vaccination Cost And Will Insurance Pay For It

Most private insurance plans cover HPV vaccination. The federal Affordable Care Act requires most private insurance plans to cover recommended preventive services with no copay or deductible.

Medicaid covers HPV vaccination in accordance with ACIP recommendations, and immunizations are a mandatory service under Medicaid for eligible individuals under age 21. In addition, the federal Vaccines for Children Program provides immunization services for children younger than 19 years who are Medicaid eligible, uninsured, underinsured, or Native American or Alaska Native.

Merck, the manufacturer of Gardasil 9, offers the Merck Vaccine Patient Assistance Program, which provides Gardasil 9 for free to people aged 19 to 45 years who live in the United States, do not have health insurance, and have an annual household income less than a certain amount.

How The Brain Responds To Pro

There are 3 specific pro-inflammatory cytokines that seem to play the biggest role in communicating between the immune system and the central nervous system. These pro-inflammatory cytokines are:

  • IL-1beta
  • IL-6
  • Tumor Necrosis Factor-alpha -This cytokine is a central regulator of inflammation and it tends to be elevated in the cerebrospinal fluid of autistic and autism spectrum children.

These three pro-inflammatory cytokines can play the good guy when the brain is functioning normally and they are present in balanced concentrations or they can play the bad guy when theyre present in elevated concentrations. These three cytokines can influence behavior in autistic children through the following mechanisms of action:

  • Other pro-inflammatory cytokines that affect neurological function
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    Dimethylsulfoxide + Reactive Oxygen Species Medicines

    Dimethylsulfoxide is an FDA approved drug that is safe for use in pregnant women, lactating women, infants, and young children. DMSO has a toxicity level that is similar to water, but dont let its low toxicity level mislead you in regard to its power. DMSO has the broadest medicinal action of any medicine currently on the books. And if its full spectrum of action were put to proper use by Big Pharma , it would change the face of medicine today and significantly reduce the toxicity while improving the power and effectiveness of drugs such as chemotherapy for cancer .

    DMSO has a special affinity for nerves and the brain. In large doses, administered via IV, it has the power to regenerate nerves. One patient, for example, who worked with Dr. Jacobs in Oregon, had a C5 cervical break after a vehicular accident. Not only did this patient survive the accident, he also WALKED out of the hospital at the end of the treatment. Downs Syndrome children who are given large, daily doses of DMSO topically develop higher IQ levels than Downs children in control groups who do not receive DMSO treatments. And young Downs Syndrome children who receive daily DMSO doses also start to lose some of the physical features associated with Downs Syndrome. These DMSO-treatment examples demonstrate the power of this medicine to heal not just nerves, but also DNA and genetic aberrations.

    How Do Hpv Vaccines Work

    Can a two

    Like other immunizations that guard against viral infection, HPV vaccines stimulate the body to produce antibodies that, in future encounters with HPV, bind to the virus and prevent it from infecting cells.

    The current HPV vaccines are based on virus-like particles that are formed by HPV surface components. VLPs are not infectious because they lack the viruss DNA. However, they closely resemble the natural virus, and antibodies against the VLPs also have activity against the natural virus. The VLPs have been found to be strongly immunogenic, which means that they induce high levels of antibody production by the body. This makes the vaccines highly effective.

    The vaccines do not prevent other sexually transmitted diseases, nor do they treat existing HPV infections or HPV-caused disease.

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    What Is The Gardasil 9 Vaccine

    Gardasil 9 is one of three HPV vaccines available worldwide. Its predecessor Gardasil has been used in New Zealand since 2008. Gardasil 9 has replaced HPV4 in the United States and will do so in New Zealand from 2017.

    Immunisation with Gardasil 9 can prevent infection with:

    • the seven HPV types that cause nine out of ten HPV-related cancers
    • the two HPV types that cause nine out of ten cases of genital warts.

    Gardasil 9 will not be offered in general practices until stocks of the existing HPV4 vaccine have run out. Many people being immunised in general practices in early 2017 will therefore be given HPV4 vaccine. HPV types 16 and 18, which are common to both vaccines, are responsible for around nine out of ten HPV-related cancers in men, which means that for men there is little practical difference between the protection offered by the two vaccines. Both vaccines also protect against nine out of ten cases of genital warts.

    It’s Easy To Get The Care You Need

    See a Premier Physician Network provider near you.

    Didnt get the HPV vaccine when you were a child or young adult? Not to worry. The U.S. Food and Drug Administration has you covered. The Gardasil 9 HPV vaccine is now approved to include men and women ages 27 to 45.

    Originally approved for ages 9 to 26, Gardasil 9 protects against the nine strains of HPV that are responsible for the majority of HPV-related cancers and diseases, including genital warts. Previous vaccine versions covered up to four HPV strains.

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    How You Can Get Hpv

    HPV which stands for Human Papillomavirus is a sexually transmitted virus that you can catch from an infected person through:

    • sexual activity, including oral sex
    • intimate skin-to-skin contact with an infected person

    You don’t have to have intercourse to get HPV.

    Without immunization, three out of four sexually active Canadians will be infected with HPV at some point in their lives.

    Second Vaccine Aimed At Reducing Cervical Cancer

    FDA Approves Use Of HPV Vaccine For Adults 27 To 45

    The World Health Organization has approved a second vaccine aimed at reducing the incidence of cervical cancer, this one made by GlaxoSmithKline, meaning UN agencies and partners can now buy millions of doses of the vaccine for poor countries worldwide.

    GlaxoSmithKline PLC said in a statement Thursday the approval would help speed access to Cervarix globally.

    The vaccine boosts immunity to the human papilloma virus, or HPV, which is responsible for most cases of cervical cancer.

    WHO had previously approved Gardasil, a competing vaccine made by Merck & Co. With two vaccines now ready to be bought by donor agencies, officials estimate that tens of thousands of lives might be saved.

    More than 80 per cent of the estimated 280,000 cervical cancer deaths a year occur in developing countries. In the West, early diagnosis and treatment has slashed the disease’s incidence.

    Last year, the global health association GAVI, formerly known as the Global Alliance for Vaccines and Immunization, prioritized the purchase of HPV vaccines for the world’s 73 poorest countries. GAVI includes U.N. agencies, the World Bank and the Bill & Melinda Gates foundation and is a major buyer of vaccines for the developing world.

    “We’re very eager to offer women in developing countries these vaccines because without early screening, they are arguably more vulnerable to cervical cancer,” said Dan Thomas, a GAVI spokesman. Thomas said the vaccine’s price was essential to making it available to poor countries.

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    Endogenous Glutamate: Can Msg Cause Autism And Post Vaccine Syndromes

    MSG is an ingredient in food that has been linked with the worsening of autism symptoms in children. A number of concerned parents throughout the world have tried to post alternative names for monosodium glutamate online that are listed on ingredient labels in different countries. The food industry works hard to cover up the presence of this ingredient in foods as monosodium glutamate has nearly 100 different names and the list keeps growing. AlivenHealthy is currently developing an app that will be able to photograph ingredient labels in any language to identify foods that contain MSG and other ingredients that cause illness. Readers are welcome to contact us at for more information about when this app will be released. We are currently looking for beta-testers for the product.

    Our bodies naturally produce glutamate, an amino acid that functions in the brain as a neurotransmitter and an excitotoxin. And there are natural sources of glutamate in food. Parents of autistic children and children with autism spectrum disorder try to avoid not just MSG, but also natural sources of glutamate because glutamate dysfunction / sensitivity can lead to a flare-up of autism symptoms.

    Vaccines can prime microglia to become over-reactive. In autistic children, the activation of microglia takes the following trajectory:

  • Just months after the first vaccine is given, the child receives additional vaccinations which triggers full microglial activation.
  • Immunity may be suppressed.
  • How Long Will The Vaccine Prevent Hpv Infection

    How long a vaccine will protect people is never known when the vaccine is first introduced. Current research shows that the vaccine is effective, and theres no sign that the protection decreases with time. Research will continue to look at how long protection against HPV lasts, and if booster shots will be needed.

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    Who Should Not Get An Hpv Vaccine Or Who Should Wait

    Pregnant women should not get any HPV vaccine at this time, even though they appear to be safe for both mother and the unborn baby. If a woman who is pregnant does get an HPV vaccine, its not a reason to consider ending the pregnancy. Women who started a vaccine series before they learned they were pregnant should complete the series after the pregnancy.

    Make sure the health care provider knows about any severe allergies. The following should not get an HPV vaccine:

    • Those with a severe allergy to yeast should not receive Gardasil or Gardasil 9.
    • Anyone who has ever had a life-threatening allergic reaction to anything else contained in the vaccines
    • Anyone who has had a serious reaction to an earlier dose of HPV vaccine

    Fewer Health Issues After Vaccination

    HPV vaccination

    To look at trends in health issues reported after HPV vaccination, the researchers turned to the Vaccine Adverse Event Reporting System , a website operated by CDC and FDA. Patients, caregivers, health care professionals, and vaccine manufacturers can use VAERS to voluntarily report any health problems that occur after vaccination.

    From 2015 to 2018, reports of health issues following HPV vaccination went down overall.

    Reports of serious health issues after HPV vaccination were consistently rarearound 1.8 per 100,000 HPV vaccine doses, or 0.0018%. A total of 758 serious health problems that arose after HPV vaccination were reported in VAERS during that time. Meanwhile, the rate of nonserious health issues following HPV vaccination reported in VAERS dropped from 43 to 28 per 100,000 vaccine doses.

    Just because a health problem is reported in VAERS doesnt mean the vaccine caused it, Dr. Sonawane cautioned. Some health reports were hearsay and lacked sufficient information to be verified, she added.

    We have to be cautious about interpreting VAERS data and not make any causeeffect associations, she said. According to CDC and FDA, VAERS data can only be used to find unusual patterns that should be evaluated in additional studies.

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    Why Should The Hpv Vaccine Be Given To Pre

    The vaccine work best at this age. Research shows that younger people have a better immune response to the vaccine than those in their late teens and early 20s. And, the vaccines will prevent the covered types of HPV only if they are given before exposure to the virus.

    This is also an age when other vaccinations are given, and when children are likely to still be getting regular medical check-ups.

    Autism And Autism Spectrum Disorders As A Post

    Autism and autism spectrum disorders develop before the age of 3-4 years of age and the symptoms can last throughout life if they are not treated withChlorine Dioxide and diet changes. Autism and autism spectrum disorders would likely be known as a Post Vaccine Syndrome if symptoms developed in adults rather than in children. Because autism / autism spectrum disorder is a syndrome that develops in children in response to vaccination, parents often accept that the disease is caused by genetics or that it has an unknown cause because their doctors tell them to believe this and every Rockefeller-funded autism organization on the planet promotes the same message. Children who develop autism symptoms are not able to question their own experience yet and their symptoms are different than the symptoms that would develop in an adult.

    Below are symptoms of autism and autism spectrum disorders. All of these symptoms are symptoms from a third-person perspective, which makes them impossible to match up with precisely with Post HPV Vaccine Syndrome or Post COVID Vaccine Syndrome. Nonetheless, scientists have noted that on a cellular level, autism and Post COVID Vaccine Syndrome have important things in common.

    • Gets upset with minor changes
    • Flaps hands, rocks the body, or spins in circles

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    How Can You Protect Yourself From Getting Hpv

    While condoms do not eliminate the risk of HPV infection, using a condom consistently and properly during vaginal, anal and oral sex decreases the chances of getting HPV or passing it on to your partner. You need to remember that a condom can only protect the area it covers so it may be possible to become infected by any uncovered warts . Using a condom will also help to protect you from other sexually transmitted infections and reduce the chances of unintended pregnancies.

    Other ways to lower your risk of infection include delaying sexual activity , limiting your number of sexual partners and considering your partners’ sexual history as this can create a risk to yourself. .

    There are now three HPV vaccines authorized for use in Canada: Gardasil®, Gardasil®9 and Cervarix®.

    Gardasil® provides protection against four HPV types: two that cause approximately 70 per cent of all cervical cancers and two that cause approximately 90 per cent of all anogenital warts in males and females . Gardasil®9 prevents up to an additional 14% of anogenital cancers caused by the additional five HPV types included in the vaccine. These vaccines are approved for use in females aged 9-45 years and males aged 9-26 years.

    Cervarix® provides protection against the two HPV types that cause approximately 70 per cent of all cervical cancers . It has been approved for use in females aged 9 to 45.

    Does Health Insurance Pay For The Hpv Vaccines

    FDA Approves New HPV Vaccine

    Insurance plans will probably cover the HPV vaccine cost if it is given according to national guidelines. But check with your insurance plan to be sure.

    The vaccines are included in the federal Vaccines for Children program. This program covers vaccine costs for children and teens who dont have insurance. The VFC program provides free vaccines to children and teens younger than 19 years of age, who are either Medicaid-eligible, American Indian or Alaska Native, or uninsured.

    The VFC program also allows children and teens to get VFC vaccines through federally qualified health centers or rural health centers. For more on the VFC program or to find the VFC contact where you live, visit, or call 1-800-232-4636.

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    What Changes To Hpv Immunisation Happened From 1 January 2017

    From 1 January 2017, HPV immunisation is funded for everyone aged 926 including boys and young men.

    Gardasil 9 will replace the existing Gardasil vaccine. The vaccine is given as two doses to those aged 14 years and under, and three doses to those aged 15 years and older.

    The vaccine is offered to boys and girls through participating schools at Year 8, around age 12. HPV immunisation is also available free through general practices from 9 years of age.

    Gardasil 9 is being used in schools from the beginning of 2017, and in general practices later in the year once stocks of the existing Gardasil vaccine have run out. Those who have begun immunisation with the existing Gardasil vaccine should complete the course with that vaccine while it is available .

    Few Young Adult Men Have Gotten The Hpv Vaccine

    But they should: A cancer found in the throat is now the leading cancer caused by HPV and 80% of those diagnosed are men.

    The COVID-19 vaccine isnt having any trouble attracting suitors.

    But theres another, older model thats been mostly ignored by the young men of America: the HPV vaccine.

    Using data from the 2010-2018 National Health Interview Surveys, Michigan Medicine researchers found that just 16% of men who were 18 to 21 years old had received at least one dose of the HPV vaccine at any age. In comparison, 42% of women in the same age bracket had gotten at least one shot of the vaccine.

    The CDCs Advisory Committee on Immunization Practices recommends two doses of the vaccine at 11 or 12 years old, but Americans can still benefit from the HPV vaccine if they receive it later, as long as they get three doses by age 26.

    In the U-M study, however even among those who were vaccinated after turning 18 less than a third of men received all three vaccine doses, and about half of women did.

    I dont think that a lot of people, both providers and patients, are aware that this vaccine is actually a cancer-prevention vaccine for men as well as women, Chen says. But HPV-associated oropharyngeal cancer can impact anyone and theres no good screening for it, which makes vaccination even more important.

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