When Is The Vaccine Given
The vaccine comes in 2 forms. The first contains inactivated cells and is given as an injection. The other contains live, weakened bacteria cells and is given as a liquid you swallow. Your healthcare provider will tell you which form is best for you. Ask when to get the vaccine if your risk is from work or contact with an infected person.
- The inactivated vaccine is given in 1 injection. Get the vaccine at least 2 weeks before you travel. This will give the vaccine time to work. You may need booster shots every 2 years if you are still at high risk for typhoid.
- The live vaccine is given in 4 doses. You will swallow 1 capsule every other day. Take the last capsule at least 1 week before you travel. This will give the vaccine time to work. You may need booster doses every 5 years if you are still at high risk for typhoid.
Who Should Get The Typhoid Vaccine
The typhoid vaccine is not required for international travel. And the vaccine is not generally recommended for people traveling to areas where the infection is common. However, the typhoid vaccine is recommended for people who travel to high-risk areas if they plan on any of the following:
- Travel “off the beaten path” in small towns and rural areas.
- Travel for more than six weeks in countries where typhoid is common.
- Travel and eat in areas without standard tourist accommodations.
How Is Typhoid Prevented
Typhoid fever is preventable. If you are traveling outside the U.S. protect yourself by taking these two basic steps:
1. Do not consume questionable drinks or food2. Get vaccinated for typhoid fever
Being mindful of what you eat and drink while travelling abroad is as important as getting vaccinated for typhoid fever mainly because the vaccine isn’t always completely effective. Not consuming risky foods may also help you avoid other illnesses like: cholera, dysentery, traveler’s diarrhea and Hepatitis A.
When traveling to parts of the world where the disease is more prevalent, consider getting immunized for typhoid fever.
To give the vaccine time to take effect, you should get immunized at least 1-2 weeks before you travel, depending on the vaccine. The vaccines for typhoid fever wear off after several years. If you have been immunized before, ask your doctor if you may need a booster dose.
Refill Prescriptions
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Who Should Not Get The Oral Vaccine
Speak with a travel clinic doctor or health care provider if you have:
- Had a life-threatening reaction to a previous dose of typhoid vaccine, or any component of the vaccine
- An immune system weakened by disease or medical treatment
- A stomach illness with nausea and vomiting
- Chronic inflammatory bowel disease or
- If you are pregnant
What Makes The Oral Typhoid Vaccine Different

Typhoid vaccination is a reliable way to help prevent typhoid fever. When used with smart eating and drinking habits, travelers are sure to feel safe.
But, there is more than one option for typhoid vaccination. It is important to choose the vaccine thats right for you. Vivotif has some differences from other typhoid vaccination options:
- Vivotif is sometimes known as an oral typhoid vaccine pill. This means you can take it on your schedule. Other injectable typhoid vaccines will need a shot. The typhoid pills are taken over a seven day period.
- Oral delivery also allows the body to form two different kinds of immune response to help protect individuals.
- The oral typhoid vaccine only requires a re-vaccination every five years. Injectable typhoid vaccines requires re-vaccination every two years.
Dont start your journey unprotected! Schedule your travel consultation today by calling or book online now. And dont forget to ask about Vivotif!
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How To Save Money And Get Better Service By Choosing The Right Travel Medicine Clinic:
Important: How To Use This Information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
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Travel Vaccines To Consider
Vaccinations are available against hepatitis A and B. Hepatitis A and B are viral infections that attack the liver. The vaccines can be given separately or as one combined vaccine. Depending on the vaccine given, the vaccine may last a lifetime or may need a booster shot in 10 to 15 years.
Canadians should have already been vaccinated against measles, mumps, rubella, diphtheria, tetanus, Haemophilus influenzae type b , pertussis, and polio as part of their routine immunization schedule. A booster shot may be required for some of these, especially the diphtheria-tetanus shot , since it provides protection for 10 years. Talk to your doctor or travel clinic to see if you’ll need a booster shot.
Flu viruses and flu vaccines vary in different parts of the world, and change every year, but the Canadian vaccine is usually a fairly typical one, and will offer a lot of protection against catching flu on most airline routes. Airplanes are extremely infectious places for respiratory diseases because, to a variable extent, the same air is continually recirculated. The flu vaccine needs to be injected every year, in the late autumn, to get full protection. Influenza is transmitted during the cold seasons in both the northern and southern hemispheres, and year-round at the equator.
Nature Of The Disease
Typhoid fever is caused by a systemic infection with Salmonella enterica subspecies enterica serovar Typhi . Paratyphoid fever, caused by infection with Salmonella enterica serovar Paratyphi A or B, is similar to typhoid fever.5 The 2 diseases are often indistinguishable.
Typhoid and paratyphoid fever are collectively known as enteric fever. Their geographic distributions largely overlap. No vaccine specifically targets paratyphoid fever, but some evidence suggests that the oral live attenuated typhoid vaccine cross-protects against Salmonella Paratyphi B.6-8
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Typhoid Fever Vaccine / Oral Typhoid Pills
If you will be traveling abroad, particularly to developing countries, the Centers for disease control and prevention recommends adults and children to take travel vaccines a week before travel. You can take typhoid vaccines at Statcare Urgent Care which has locations in Hicksville, Long Island Astoria, Queens Brooklyn, NYC the Bronx at Bartow Avenue the Bronx at E. 174th Street Jackson Heights, the Queen Midtown Manhattan in Manhattan and Jamaica, Queens. This vaccine will fully protect you from getting this diarrheal disease which usually also leads to a chronic typhoid carrier state. Side effects and allergic reactions with the oral typhoid vaccine are very uncommon.
What Is Typhoid Fever Vaccination
- Oral live-attenuated vaccine
- Injectable, combined with hepatitis A
In some typhoid-endemic countries with poor sanitation, new conjugate typhoid vaccines are now available to prevent typhoid fever. This formulation is given to adults aged 45 years old down to infants from 6 months of age, offering at least 3 years of protection These typhoid fever vaccines are not yet licensed in Australia.
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How Can I Reduce My Chances Of Getting Typhoid
The best way to prevent typhoid infection is to get vaccinated. You may try to protect yourself from this infection by doing the following:
- Wash your hands with soap often
- Drink safe, adequately chlorinated water
- Eat at reputable places
- Eat food while it is still hot or boil or cook what you drink and eat for at least one minute at 185 °F
What Causes Typhoid Fever

Typhoid fever is an acute illness associated with the fever caused by the bacteria Salmonella typhi. It can also be caused by Salmonella paratyphi, a related bacterium that usually causes a less severe illness. The bacteria that causes typhoid are left in water or food by a human carrier, which is then spread to others who come in contact with the bacteria left behind.
Typhoid fever in the US has been mostly eradicated since the early 1900s, when tens of thousands of cases were reported annually. Today, less than 400 cases are reported each year in the US, and these mostly from travelers who have recently been to Mexico and South America, and to a lesser extent India, Pakistan and Egypt.
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Who Should Get The Vaccine
People travelling to or working in South Asia including Afghanistan, India, Nepal, Bangladesh, Maldives, Sri Lanka and Bhutan for 3 weeks or more may need to get the vaccine. You are more likely to be exposed to contaminated food and water in these high risk areas.
If you are travelling to low risk areas, including Africa, Asia, the Caribbean, Central and South America, the travel clinic doctor or nurse will tell you if you should receive the vaccine.
The vaccine is also recommended for:
- Workers routinely exposed to typhoid bacteria, such as certain researchers and lab employees
- People who live in the same house or have sexual contact with a typhoid carrier
Booster Doses Of Vivotif
The product information for Vivotif Oral live attenuated vaccine recommends a booster every 3 years.
For people at ongoing risk of typhoid fever, ATAGI also recommends revaccination with a 3- or 4-dose course of the oral live attenuated vaccine 3 years after a 3-dose course, or 5 years after a 4-dose course.
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Where Can You Catch Typhoid
Typhoid infections are common in Mexico, East and South Asia , South America and Africa. An estimated 22 million cases and 200,000 to 600,000 deaths occur worldwide each year.
Typhoid bacteria are ingested in contaminated food or water. They can be avoided by drinking only bottled water, and avoiding ice, unpeeled fruits, undercooked meats, shellfish, salads and food from street vendors.
How Should I Use This Medicine
Take this medicine by mouth with a glass of water. Take this medicine on an empty stomach, at least 1 hour before food. Do not take with food. Do not cut, crush or chew this medicine.
A copy of Vaccine Information Statements will be given before each vaccination. Read this sheet carefully each time. The sheet may change frequently.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Preparations Authorized For Use In Canada
Typhoid-containing vaccines
- TYPHIM Vi® , Sanofi Pasteur SA , Sanofi Pasteur Ltd.
- ViVAXIM® , Sanofi Pasteur SA , Sanofi Pasteur Ltd.
- Vivotif® ,PaxVax Berna GmbH. , Crucell Vaccines Inc.
There are no authorized vaccines to protect against S. paratyphi infection .
For complete prescribing information, consult the product leaflet or information contained within the product monograph available through Health Canadas Drug Product Database.
Refer to Contents of Immunizing Agents Authorized for Use in Canada in Part 1 for a list of vaccines authorized for use in Canada and their contents.
Ty21a Live Oral Vaccine
Ty21a provides significant protection and appears to be quite safe.121,149,245,279,280,382 Results of three double-blind, placebo-controlled studies that used active surveillance methods to assess the reactogenicity of Ty21a in adults and children are shown in Table 61.14. Surveillance methods to assess the reactogenicity of Ty21a in adults and children are shown in Table 61.14. The rates of adverse reactions in the vaccine recipients were not significantly higher than those for the placebo group for any symptom or sign. In large-scale field trials with Ty21a, involving approximately 550,000 schoolchildren in Chile and 32,000 schoolchildren in Egypt, and approximately 20,000 subjects ranging in age from 3 years to adulthood in Indonesia, passive surveillance failed to identify vaccine-related adverse reactions.121,124,218,230,245,383
Rick D. Kellerman MD, inConn’s Current Therapy 2021, 2021
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What Should I Discuss With My Healthcare Provider Before Receiving Typhoid Vaccine
You should not receive this vaccine if you have ever had an allergic reaction to typhoid vaccine in the past, or if you have:
- a fever with any type of infection or illness or
- weak immune system caused by disease or by using certain medicine.
If you have any of these other conditions, your vaccine may need to be postponed or not given at all:
- stomach flu or any illness with vomiting or diarrhea
- if you are taking an antibiotic, especially a sulfa drug or
- if you plan to start taking anti-malaria medicine within 10 days after receiving a typhoid oral vaccine.
You can still receive a vaccine if you have a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.
It is not known whether typhoid vaccine will harm an unborn baby. However, if you are at a high risk for infection with typhoid fever during pregnancy, your doctor should determine whether you need this vaccine.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
Some History Of Typhoid Fever:

In the early 1900’s the famous case of Mary Mallon or “Typhoid Mary” occurred in the New York area. In summary, Mary was a distinguished housekeeper and cook hired by a number of wealthy families. Unfortunately, the concept that microscopic germs could cause disease was a very new and controversial idea. Mary carried the bacteria but did not know it and consequently is believed to have infected and inadvertently caused severe illness and death of a number of people. Public Health authorities cultured the bacteria and traced it to Miss Mallon. It was the first case of typhoid transmission in the USA.
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What Should I Avoid Before Or After Using Typhoid Vaccine
Avoid eating anything for at least 1 hour after you take a capsule.
Do not drink alcohol within 2 hours after you take a typhoid vaccine capsule. Alcohol can damage the capsule and could make the vaccine ineffective.
In addition to using this vaccine, take precautions while traveling to further prevent coming into contact with bacteria that cause typhoid fever:
-
Avoid eating leafy vegetables such as spinach or lettuce, which are harder to wash properly.
-
Avoid eating raw fruits or vegetables that cannot be peeled, or that have been peeled by another person.
-
Avoid drinks that contain ice, or frozen treats and flavored ices that may have been made with contaminated water.
-
Avoid eating foods you have not cooked or prepared yourself. Use clean surfaces and utensils when preparing food.
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Drink only bottled water or water that has been boiled for at least 1 minute.
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Avoid any food or beverage purchased from a street vendor.
How Is Typhoid Spread
The infection is transmitted through contaminated water and food.
Risky areas
Typhoid is more common in rural areas. However, those who visit cities can easily become infected too.
Seasonality
People get typhoid fever year-round, but there are some seasonal patterns that vary from region to region. Please see the table below.
Region |
---|
- Staying with a local family
- Adventurous eating
- Eating food prepared or touched by a typhoid-positive person
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Where To Get The Typhoid Fever Vaccine
Pharmaca has been providing immunization services recommended by the CDC for many years. We have locations in six states, and even offer some immunizations and vaccinations on a walk-in basis.
If youre traveling, or think you may be in a position to need a typhoid fever vaccination, to set up an appointment to get your next vaccine.
Thinking of getting a typhoid vaccination? to schedule an appointment.
What Is Typhoid Vaccine
Typhoid is a serious disease caused by Salmonella typhi bacteria. Untreated typhoid infection may lead to kidney failure, or intestinal bleeding, which can be fatal. If the infection spreads to your gallbladder, you could become a chronic carrier of the bacteria that causes typhoid. A carrier may have no symptoms but is capable of spreading the infection to others.
Typhoid is spread through contact with the stool of a person infected with the bacteria. This usually occurs by eating food or drinking water that has become contaminated with feces from an infected person. Once in the digestive tract, typhoid infection can spread to the blood and other parts of the body.
Typhoid can cause high fever, muscle aches, severe headache, weakness, confusion or agitation, loss of appetite, stomach pain, diarrhea or constipation, and rose-colored spots on the skin.
Typhoid vaccine is used to help prevent this disease in adults and children who are at least 6 years old. Although not part of a routine immunization schedule in the U.S., typhoid vaccine is recommended for:
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people who travel to area where typhoid fever is common
-
people who live with someone who is a typhoid carrier and
-
laboratory workers who may come into contact with Salmonella typhi in a work setting.
This vaccine works by exposing you to a small amount of the bacteria, which causes your body to develop immunity to the disease.
Like any vaccine, the typhoid vaccine may not provide protection from disease in every person.
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